乙胺丁醇

DNA芯片快速检测结核分枝杆菌对链霉素和乙胺丁醇的耐药性方法的建立

Rapid detection of M.tuberculosis resistance to SM and EMB by the Gene Chip method

噬菌体法与BACTEC-960检测结核分枝杆菌乙胺丁醇耐药性的比较研究

Comparison between bacteriophage-based assay and BACTEC-960 system in detection of ethambutol resistance in Mycobacterium tuberculosis

目的应用膜反向斑点杂交技术快速检测结核分枝杆菌对乙胺丁醇（EMB）耐药性。

[ Objective ] To study the rapid detection of resistance to ethambutol in mycobacterium tuberculosis by reverse dot blot hybridized technique .

目的：探讨结核分枝杆菌对乙胺丁醇（EMB）产生耐药性的分子机制，建立直接快速检测结核分枝杆菌EMB药物敏感性的实验方法。

Objective : To research the molecular mechanism of M.tuberculosis resistance to Ethambutol , and to set up a method for direct , rapid detection of Ethambutol resistance gene mutations in M.tuberculosis .

这四种抗生素分别是异烟肼、利福平、吡嗪酰胺和乙胺丁醇。南非的科学与工业研究理事会（CSIR）的科学家已经把这些药物放入了肉眼不可见的纳米颗粒中。

South African scientists from the Council for Scientific and Industrial Research ( CSIR ) have incorporated these drugs into nanoparticles that are invisible to the human eye .

当乙胺丁醇作用于M.TB后，M.TB的细胞壁中阿拉伯糖大量流失，细胞壁结构遭到破坏。

After treated with EMB , arabinose in cell wall of TB was lost greatly , and the structure of the cell wall was destroyed .

方法：采用明胶和聚己内酯复合包裹法将异烟肼、利福平、吡嗪酰胺和乙胺丁醇等4种抗结核药物按一定浓度和配比与重组合异种骨（RBX）复合，制备抗结核骨。

Method : Anti-TB bone was made of reconstituted bone xenograft ( RBX ) combined with 4 antituberculosis drugs ( Isoniazide , Rifampicin , Pyrazinamide , Ethambutol ) at certain concentration and encapsulated by gelatin and polycaprolactone .

结果以Bactec-960检测结果为判断标准，液体培养基比色法检测链霉素、异烟肼、利福平和乙胺丁醇耐药性结果与Bactec-960的符合率分别为100.0%、96.9%、98.1%和97.5%。

Results If the results of Bactec-960 system is the golden standard , the accuracy of colorimetric method assay for testing susceptibility of MTB to streptomycin , isoniazid , rifampicin and ethambutol was 100.0 % , 96.9 % , 98.1 % and 97.5 % respectively .

乙胺丁醇致手指甲紫绀、舌下溃疡及视力减退

Nail cyanosis , sublingual ulcer and visual deterioration caused by ethambutol

结核分枝杆菌乙胺丁醇耐药的分子机制及其快速鉴定

Molecular mechanism and rapid identification of ethambutol - resistant Mycobacterium tuberculosis

特异性核酸内切酶检测结核分枝杆菌的乙胺丁醇耐药基因突变

Analysis of ethambutol drug-resistance gene mutation in Mycobacterium tuberculosis by specific endonuclease

乙胺丁醇中毒性视神经病变21例临床分析

Twenty-one cases clinical analysis of changes in toxic optic nerves by ethambutol

4株为多耐药株结核杆菌（对异烟肼、利福平、链霉素、乙胺丁醇4种药物均耐药）；

Four strains were multi - drug - resistant ;

目的：建立旋光法测定盐酸乙胺丁醇片含量的方法。

To establish an accurate method for the determination of ethambutol hydrochloride tablet .

其它两种药物是乙胺丁醇和吡嗪酰胺。

The other two medicines are Ethambutol and Pyrazinamide .

乙胺丁醇&磷酸钙骨水泥复合体药物释放系统的研究

Study on Drug Delivery System of Ethambutol-Calcium Phosphate Cement-Compound

小剂量乙胺丁醇致中毒性视神经病变

Toxic Optic Neuropathy Induced by Small Dosage of Ethambutol

最常用的抗结核药品是异烟肼、利福平、吡嗪酰胺和乙胺丁醇。

The most common anti-TB medicines are isoniazid , rifampicin , pyrazinamide and ethambutol .

目的探讨乙胺丁醇中毒性视神经病变的防治。

Objective To investigate the prevention and treatment for changes in toxic optic nerves .

对照组用链霉素，异烟肼对氨基水杨酸钠、利福喷汀、乙胺丁醇、吡嗪酰胺，疗程均为18个月。

The course of treatment was 18 months .

对照组用链霉素、乙胺丁醇，联用药物同治疗组，疗程均为21个月。

The course of treatment was 21 months .

乙胺丁醇是手性抗结核药物盐酸乙胺丁醇的关键中间体，本文详细介绍了乙胺丁醇的两种合成方法：直接法和间接法。

Ethambutol is the key intermediate of ethambutol hydrochloride used as a chiral antituberculosis agent .

乙胺丁醇中毒性视神经损害

Optic nerve neuropathy by ethambutol toxicity

乙胺丁醇的合成研究进展

Progress on Synthesis of Ethambutol

对每例进行异烟肼、利福平、吡嗪酰胺、乙胺丁醇、链霉素的斑贴试验。

Each cases was conducted the patch test of Isoniazid , Rifampicin , Pyrazinamide , Ethambutol streptomycin .

用反向斑点杂交法检测结核杆菌对链霉素和乙胺丁醇的耐药性

Detection of drug-resistances of Mycobacterium tuberculosis isolates to streptomycin and ethambutol by a new method of reverse dot blot

乙胺丁醇处理前后耻垢分枝杆菌mc~2155细胞蛋白双向电泳图谱的差异分析

Simultaneous detection of proteins expression of Mycobacterium smegmatis mc ~ 2155 after treatments of ethambutol ( EMB ) by two-dimensional electrophoresis

科学家比较了巴西里约热内卢的170位结核病患者服用莫西沙星和乙胺丁醇的效果。

Researchers compared the efficiency of using the moxifloxacin and ethambutol antibiotics in170 TB patients in Rio de Janeiro , Brazil .

比例法药敏试验检测乙胺丁醇耐药适合药物浓度的初步探讨

Preliminary study on the appropriate concentrations of drug used in the drug-susceptibility test to detect the Ethambutol-resistant isolates of Mycobacterium tuberculosis

结核病的一线疗法由每天服用含有4种抗生素的药片组成。这四种抗生素分别是异烟肼、利福平、吡嗪酰胺和乙胺丁醇。

First-line treatment for TB consists of a pill of each of four antibiotics isoniazid , rifampicin , pyrazinamide and ethambutol taken every day .