mele

Pharmacokinetics and Bioavailability of MELE & A New Antihypertensive Drug in Rats

抗高血压新药美林洛尔在大鼠体内的药代动力学和生物利用度

The absolute bioavailability of MELE in rats was 40.74 % .

美林洛尔在大鼠体内的绝对生物利用度为40.74%。

Mele pays special attention to the fourth estate .

梅勒给予了新闻界特殊关注。

As Mele acknowledges , the book goes wide rather than deep .

梅莱承认，这本书着眼的重点是广度，而不是深度。

Van Mele says they intend to take the research to other African countries , including East Africa .

VanMele说他们打算在其他非洲国家进行这项研究，包括东非国家。

Conclusion : There 's difference of clinical symptom and prognosis between MELE and FSLE .

结论：男性与女性SLE的临床表现及预后有一定差异，应引起重视。

While new technology has given the once overlooked little guys more power , Mele cautions that it comes with unintended consequences .

尽管新科技赋予了那些曾经被忽视的小公司更大的能量，尼科•梅莱却告诫说，这将会导致预料之外的后果。

Paul Van Mele and colleagues published their work in the June edition of the Journal of Economic Entomology .

PaulVanMele和他的同事在6月出版的《经济昆虫学杂志》上发表了他们的这项研究成果。

Did you ask Mele , too ?

你还问过米勒了？

METHODS The binding rate of MELE to human plasma proteins was determined by equilibrium dialysis method . Concentration of MELE was assayed by HPLC with fluorescent detection .

方法：用平衡透析法测定血浆蛋白结合率，用高效液相-荧光检测法测定血浆中药物总浓度及游离药物浓度。

RESULTS The binding rate of MELE to plasma protein was found to be ( 7.02 % ) - ( 18.75 % ), varying with the concentration of MELE .

结果：美林洛尔与人标准血浆的蛋白结合率随药物浓度发生变化约为7.02%~18.75%。

In2005 , Charles Kane and Eugene Mele of the University of Pennsylvania in Philadelphia did away with half of that objection .

年，来自费城宾夕法尼亚大学的查尔斯·凯恩和尤金·梅莱消除了一半的阻碍。

OBJECTIVE To develop a high - performance liquid chromatographic ( HPLC ) method to determine the concentration of MELE in human plasma . To study the binding rate of MELE to plasma proteins , and to calculate the binding parameters of MELE to plasma proteins .

目的：建立人标准血浆中美林洛尔（MELE）浓度的测定方法，测定美林洛尔在人标准血浆中的蛋白结合率，并计算相关参数。

The creatine phospho kinase ( CP K ) activiity of umbilical cord blood in 4118 mele newborns was determined . The results showed that mean CPK activty in 4118 male newborns is 27.5 U / ml ( SD . 18.6 ) .

本工作测定了4118例男性新生儿脐带血血清CPK活力，平均值为27.5U/ml（SD.18.6）。