dimenhydrinate

Determination of dimenhydrinate by computeraided convolution curve method

计算机辅助褶合曲线分析法测定茶苯海明含量

Improved-JP dissolution disintegrating method was optimum for the measurement dimenhydrinate ODT .

对于茶苯海明口崩片，则以日本药典（JP）溶出度改良法较为适合。

Dry ginger root powder has marked anti-sea-sickness effect which is stronger than dimenhydrinate .

干姜粉具有明显的抗晕船作用，其效果强于晕海宁。

OBJECTIVE To prepare dimenhydrinate ( DMH ) orally disintegrating tablets with fast dissolution rate and good taste .

目的制备既可掩盖苦麻味又能快速崩解的茶苯海明口腔崩解片。

A trademark used for dimenhydrinate .

德拉马明晕海宁的一个商标。

The present method provides accurate and reliable results comparable to those obtained from the assay defined in the Chinese Pharmacopeia ( 1985 ) for five batches of dimenhydrinate .

五批商品测定值与中国药典（1985年版）结果一致。

Results : While monitoring dissolution of drug products , one can tell the difference of Amoxicillin and Dimenhydrinate and identify photolysis products of Extended Release Nifedipine Tablets by absorption spectrum displayed in a real-time manner .

结果：在溶出度过程监测的同时，实时显示的吸收光谱可分辨阿莫西林和茶苯海明不同药物的真伪，硝苯地平缓释片光解产物的鉴别。

Dimenhydrinate ( DMH ), a histamine H_1-receptor antagonist , is widely used in the treatment of giddy , irritability , pollenosis and urticaria .

茶苯海明为一种组胺H1受体拮抗剂，主要用于抗晕动，也用于过敏性疾病，如枯草热、荨麻疹。

Results shown that T_ ( 50 ) and T_d compared with disintegration time were very significantly correlated ( p < 0.01 ), Therefor it may be regarded as the reference standard for dissolution rate of dimenhydrinate tablet .

值进行了方差分析，经实验认为T（50）、Td值与崩解时限间具有高度相关性（P<0.01），同时对国内同类产品的溶出度提出了参考标准。