diazoxide

Effects of Diazoxide on Acute Myocardial Infarction in Old Rabbits

二氮嗪对老年大兔心肌梗死影响的研究

The protective effect of diazoxide on long-term heart preservation

二氮嗪在长时程心脏低温保存中的作用

Protective effect of diazoxide preconditioning on ischemia and reperfusion isolated working rat heart

二氮嗪预处理对大鼠离体缺血/灌注心肌保护作用的研究

Effect of diazoxide on apoptosis induced by myocardial ischemia / reperfusion injury in rats

二氮嗪对大鼠心肌缺血-再灌流损伤细胞凋亡的影响

Influence of Diazoxide to Isoprenaline-Induced Apoptotic Gene Expression of Rat Myocardial Cell

二氮嗪对异丙肾上腺素诱导的大鼠心肌细胞凋亡相关基因表达的影响

Delayed Preconditioning By Diazoxide Decrease Myocardial Apoptosis on an in vivo Rabbit Model

药物延迟预处理减少在体幼兔缺血再灌注损伤后的心肌细胞凋亡

Protective Effects of Diazoxide on Injury of Human Renal Tubular Cell Induced by Serum Obtained from Neonates with Asphyxia

二氮嗪对新生儿窒息后血清诱导人近曲肾小管上皮细胞损伤的保护作用

Diazoxide increases glutamate uptake by astrocytes via activating mitochondrial ATP-sensitive potassium channels

线粒体K（ATP）开放剂二氮嗪促进星形胶质细胞摄取谷氨酸

An experimental study on the effects of diazoxide in combination with fructose 1,6-diphosphate on heart preservation in rats

二氮嗪与1,6-二磷酸果糖伍用对大鼠心脏保存作用的初步研究

CONCLUSION : Modulation by diazoxide on functions of rat cardiac mitochondria is associated with its anti - ischemic efficacy .

结论：二氮嗪可调节大鼠心肌线粒体功能，这与其抗心肌缺血保护作用有关。

Clinical observations of diazoxide treatment in hyperinsulinism

二氮嗪治疗高胰岛素血症的临床观察

Diazoxide ( mitochondrial K_ ( ATP ) channel opener ) + H / R ;

diazoxide（线粒体KATP通道开放剂）+H/R组；

Influence of k ￣ + concentration and diazoxide on histamine release induced by 4-aminopyridine from rat peritoneal mast cells

K~＋浓度和二氮嗪对4－氨基吡啶诱发大鼠腹腔肥大细胞释放组胺的影响

OBJECTIVE To investigate the effect of diazoxide on expression of ICAM-1 and TNF - α during ischemia-reperfusion in rat cardiac muscles .

目的研究二氮嗪（DZ）开放线粒体ATP敏感性钾通道对缺血再灌注损伤所致大鼠心肌组织ICAM-1和TNF-α表达的影响。

Objective To investigate whether diazoxide preconditioning can exert protective effect on myocardium against ischemia-reperfusion injury in immature rabbits and the possible mechanism .

目的了解二氮嗪预处理对未成熟兔心脏有无保护作用，并探讨其机制。

Influence of diazoxide inhibition of A β _ ( 1-42 ) on cellular survival rate , mitochondrial membrane potential and intracellular ROS level

二氮嗪抑制Aβ（1～42）对U251细胞存活率、线粒体膜电位和细胞内活性氧水平的影响

Objective To investigate whether K + channel opener diazoxide could protect cells from A β 1-42-induced cytotoxicity and its molecular mechanism .

目的探讨线粒体膜上ATP敏感的钾离子通道开放药物二氮嗪防治Aβ1～42细胞毒性作用及其分子学机制。

It suggested that earlier diazoxide could protect mitochondrial function and prevent nerve cells decreasing cell induced by cell apoptosis in long-term A β 1-42 exposure .

提示尽早应用二氮嗪保护细胞线粒体功能状态，可预防长时间暴露于Aβ1～42导致细胞凋亡所引起的神经细胞数量的减少。

In Group DP , the rabbits were pretreated intravenously with diazoxide ( 3 mg / kg ) .

DP组在缺血前缓慢静脉注射二氮嗪3mg/kg。

Investigation of relationship between dose of diazoxide and protection of preconditioning by diazoxide from isoproterenol injury in adult rat cardia

二氮嗪预处理对成年大鼠心肌异丙肾上腺素损伤的保护作用及其与剂量的关系

The Study of Diazoxide 、 Cyclosporine A to Antagonize Apoptosis Induced by A β _ ( 1-42 ) on Cholinergic Neurons

二氮嗪、环孢菌素A拮抗Aβ（1-42）致胆碱能神经元凋亡的研究

We have reported that diazoxide as a supplementation in Celsior preservation solution , can improve myocardial function and decrease apoptosis during long - term hypothermic preservation .

研究发现在Celsior心脏保存液中添加二氮嗪，能促进长时低温保存后心功能的恢复并减少心肌细胞凋亡。

Objective To determine the delayed protective effect of diazoxide ( DE ), as an ischemic preconditioning ( IPC ) simulator , on inhibition of ischemia / reperfusion induced hepatocyte apoptosis in rats .

目的探讨二氮嗪（DE）预处理模拟缺血预处理（IP）抑制肝缺血再灌注（I/R）损伤所致细胞凋亡的延迟保护（DP）作用及其可能机制。

In Group DP , the rabbits were pretreated intravenously with diazoxide ( 3mg · kg ~ ( - 1 )) 30 minutes prior to LAD occlusion .

DP组在40分钟缺血前30分钟接受3mg·kg~（-1）的二氮嗪缓慢静脉注射。

Influence of different protective methods on moisture ratio in pig brain with deep hypothermic circulatory arrest The Study on Preconditioning with Diazoxide Ameliorates Neurological Injury in the Early Period Induced by Deep Hypothermic Circulatory Arrest

深低温停循环时不同脑保护方法对猪大脑组织含水率的影响二氮嗪预处理对深低温停循环脑早期保护作用的实验研究

Diazoxide ( 30mg / kg ) and glipizide ( 5mg / kg ) are administered to the rat model respectively . The metabolism characteristics are measured and pancreatic histopathology is analyzed among each group .

二氮嗪（30mg/kg），格列吡嗪（5mg/kg）分别干预糖尿病大鼠模型，检测各组的生化指标，胰腺组织HE染色以及胰岛细胞凋亡，对比各组大鼠间胰岛细胞病理学的差异。

Objective : To investigate whether the mitochondrial ATP-sensitive potassium channel ( mitoK_ ( ATP )) opener diazoxide as an additive to cardioplegia solution could enhance myocardial protection during hypothermic preservation of the rat heart .

目的：探讨线粒体ATP敏感性钾通道开放剂二氮嗪（DE）对离体大鼠心脏冷保存效果的影响及作用机制。