LDLR

Comparison of abundance of LDLR mRNA in liver of periparturient dairy cows intaking different energy

摄入不同能量的围产期乳牛肝低密度脂蛋白受体mRNA丰度的比较

Additionally , p38 may play a critical role in cholesterol metabolism by regulating expression of the LDLR gene and bile metabolism .

另外，p38还通过调节低密度脂蛋白受体基因表达和胆汁代谢对胆固醇代谢起关键作用。

Research on Expression and Regulation of the Low Density Lipoprotein Receptor ( LDLR ) Gene

低密度脂蛋白受体基因表达调控研究

The reduced expression of LDLR gene is responsible to carotid atherosclerosis .

LDLR表达减少参与了颈动脉粥样硬化的发病过程。

Study of LDLR activity of murine hepatoma 22 cells

小鼠肝癌H（22）细胞LDLR的分析研究

Conclusions LDLR gene polymorphism might be associated with EH accompanied obesity .

结论LDLR基因多态性可能与EH伴肥胖相关。

Expression of LDLR Gene in Monocytic Cells in the Patients with Carotid Atherosclerosis

颈动脉粥样硬化病人血单个核细胞中低密度脂蛋白受体基因表达的研究

Effects of berberine on the expression of LDLR in human liver cell strain Bel - 7402

盐酸小檗碱对人肝Bel-7402细胞株LDLR表达的影响

Effects of Different Doses of Daidzein on Serum Lipids and Liver LDLR Expression in Ovariectomized Rats

大豆苷元对去卵巢大鼠血脂及肝脏ERα和LDLR表达的影响

LDLR is closely related to cholesterol metabolism and cleans the cholesterol in blood .

LDLR与脂代谢关系密切，血浆中胆固醇主要是由肝细胞表面的LDLR清除。

Direction of the Human LDLR Gene Sites by RFLPs and its relation to FH

LDLR基因位点的RFLPs检测及其与FH的相关性

Deviant structure and function of LDLR will result in serious diseases such as coronary heart disease , atherosclerosis .

LDLR结构和功能的紊乱将导致严重的冠心病、动脉粥样硬化等疾病。

Study on LDLR Gene 1972 T / C SNP and MTHFR Gene 677 C / T SNP

LDL受体基因1972T/CSNP及MTHFR基因677C/TSNP研究

[ Conclusion ] C allele of LDLR could play a role in the pathophysiology of elderly obese hypertension .

结论LDLR的C等位基因可能在老年肥胖性高血压的发病机制中发挥作用。

㏕ o investigate whether Xenopus Oocyte have endogenetic LDLR with PVS Sedimentation and Fluorescence detection .

以PVS沉淀法和荧光免疫检测法，考察爪蟾V、V工期卵母细胞是否有内源性的LDLR。

Molecular and pathological characteristics of AS plaque formation induced by high-fat diet of LDLR and the APOE gene knock-out mice

高脂饮食诱导APOE和LDLR基因敲除鼠AS斑块形成的分子病理学特征

It obviously increase the presence of LDLR in rats ' liver of model group , showing obvious difference from the model group ( P < 0.05 ) .

显著增加LDL-R在大鼠肝脏的表达，与模型组比较有显著性差异（P＜0.05）；

Conclusions FH is an euchromosome dominant genetic disease that is caused by the defective LDLR resulted from gene mutation .

结论：FH是一常染色体显性遗传性疾病，为基因突变导致LDLR缺陷所致的遗传性疾病。

The functional defect of low density lipoprotein receptor ( LDLR ) gene is one of the main reasons that lead to hyperlipidemia and atherosclerosis .

低密度脂蛋白受体（LDLR）基因功能缺陷是引起血脂异常及动脉粥样硬化的主要原因之一。

Objective To screen the mutations of low-density lipoprotein receptor ( LDLR ) gene in Chinese familial hypercholesterolemia ( FH ) patients .

目的调查我国家族性高胆固醇血症（FH）患者低密度脂蛋白受体基因突变类型。

Has obvious effect of reducing fat resulting from high-fat diet and its chemical components are endowed with the role of stimulating the expression of LDLR .

结论：烈洗对高脂饮食诱导的肥胖具有明显的治疗作用，其所含化学成分具有促进低密度脂蛋白受体表达的作用。

Conclusion ( 1 ) There are not endogenetic LDLR on membrane of Xenopus Oocyte of phase V , VI.

结论①爪蟾V、VI期卵母细胞未见内源性LDLR，不存在对外源人类LDLR基因表达的干扰作用。

Results : The LDL activity of gastric adenocarcinoma is obviously higher than the normal gastric tissues , but affinity and specificity of LDLR don 't obviously change .

结果胃腺愿组织的LDLR活性明显高于其周边正常组织，但其LDLR的亲和性和特异性无明显改变；

Together , these results suggest that LXR can control cholesterol homeostasis through regulating IDOL expression and eliciting IDOL mediated LDLR degradation in vivo .

综上，这些结果表明：在体内，LXR能够通过调节IDOL表达和激活IDOL介导的低密度脂蛋白受体的降解以实现胆固醇稳态的控制。

Previously , we have observed that CRH dramatically increased VCAM-1 mRNA and protein expression in LDLr - / - mice and promoted the development of atherosclerosis .

本实验室研究发现，CRH可显著增加LDLr-/-小鼠VCAM-1mRNA和蛋白表达，促进小鼠动脉粥样硬化发展。

The sterol response element ( SRE ) of the LDL receptor promoter is responsible for normal sterol regulation and the expression of LDLR gene .

低密度脂蛋白受体（LDLR）调节体内胆固醇的平衡是通过其启动区的固醇调节元件（SRE）感受体内胆固醇的变化，从而调控LDLR基因的表达来实现的。

Results : Curcuma could enhance the LDLR on the membrance of macrophage , and the number of LDLR increased when the concentration of curcuma increased .

结果高中低三个剂量的姜黄素均能使巨噬细胞膜上LDL受体数量增加，随姜黄素浓度增加，LDL受体数量也明显增加。

Study showed that LDLR in dyslipidemia patients was defective in function and injured in different degree , which resulted in the plasm levels of low density lipoprotein increasing and atherosclerosis .

研究表明，高胆固醇血症患者存在LDLR功能缺陷和不同程度的损伤，导致血浆中低密度脂蛋白水平升高，形成动脉粥样硬化。

In order to investigate the anti-atherosclerotic mechanism of Livial , the expression of ERa and LDLR mRNA in heart and liver were analyzed by real-time quantitive RT-PCR .

为了研究利维爱防治动脉粥样硬化发展的部分机理，采用荧光定量RT-PCR技术，对与AS发生密切相关的ERa和LDLRmRNA在心脏和肝脏内的表达进行定量分析。

The radioreceptor binding assay showed that haw and flavonoids could increase hepatic LDLR density , but could not change the affinity of LDL to hepatic membrane LDLR .

放射性配体结合力试验表明，山楂及山楂黄酮显著增加了大鼠肝脏LDLR数目，而对亲和力影响不明显。