Glibenclamide

The Effect of Low Dose Glibenclamide on Secondary Lesion of Rat with Acute Spinal Cord Injury

小剂量格列本脲对大鼠急性脊髓损伤后继发性损害的影响

To establish a method of determine the dissolution of glibenclamide .

建立格列本脲溶出方法。

Improvement in Content Uniformity and Dissolution Uniformity of Glibenclamide with Solvent Dispersing Method

溶剂分散法改善格列苯脲含量均匀度及溶出均一性

Re evaluation of the maximal dose of glibenclamide recommended in NIDDM patients

重新评估格列本脲（优降糖）最大剂量的初步研究

Objective : To prepare the compound glibenclamide tablets .

目的：制备复方格列本脲片。

Determination of Three Related Substances in Metformin Hydrochloride and Glibenclamide Tablets by HPLC

HPLC测定复方盐酸二甲双胍格列苯脲中3种有关物质

Effects of metformin or glibenclamide combined with insulin in the patients with type 2 diabetes mellitus

胰岛素联合二甲双胍或优降糖治疗2型糖尿病的疗效比较

Determination of two components in metformin hydrochloride and glibenclamide tablets by ion-pair HPLC method

二甲双胍格列本脲片中两种成分的离子对HPLC法测定格列美脲与格列苯脲治疗2型糖尿病的临床观察

Effects of nucleotides on the binding sites for glibenclamide in rat cardiac ventricular membranes

核苷酸对大鼠心肌[~3H]格列本脲结合位点的影响

OBJECTIVE To establish an HPLC method for determining glibenclamide in Xiaokeping granules .

目的建立测定消渴平颗粒中格列本脲含量的方法。

Results Among 36 patients with hypoglycemia coma , 19 ( 52.8 % ) took glibenclamide ;

结果36例糖尿病低血糖昏迷中，19例服用优降糖，占528%；

Regulation of Pial Artery by Glibenclamide During Cortical Spreading Depression in Rats

格列本脲对大鼠皮层扩散性抑制中脑血管的调节作用

Preparation of Glibenclamide Solid Dispersion and Compound Glibenclamide Capsules

格列本脲固体分散体及其复方胶囊剂的研制

Different responses of β cell to glucagon and glucose in type 2 diabetic patients with secondary failure to glibenclamide

优降糖继发失效患者对葡萄糖及胰升糖素的不同反应

Preparation and Characterization of Hydroxypropyl - β - cyclodextrin / Glibenclamide Inclusion Complex

羟丙基-β-环糊精/格列本脲包结物的制备及其表征

Glibenclamide was used in B and D groups to inhibit ATP-sensitive potassium channels before ischemia .

其B和D组在缺血前以优降糖阻止心肌ATP敏感性钾通道的开放。

The solubility results of inclusion complex in water indicated that the solubility of glibenclamide increased by15 times .

包结物的水溶性实验结果表明包结后格列本脲的溶解度增加了15倍。

Preparation of compound metformin hydrochloride glibenclamide tablets Biological transport of glybenclamide by two kinds of osteoblasts

复方盐酸二甲双胍格列本脲片的研制比较两种成骨细胞对格列本脲的转运

Influence of glibenclamide on ATP-sensitive potassium channels in the cardiac ischemic preconditioning against myocardial ischemia-reperfusion injury

优降糖对K（ATP）通道介导缺血预适应心肌再灌注损伤的影响

Effects of glibenclamide on mRNA level of ATP-sensitive potassium channels of heart in normal and streptozotocin induced diabetic rats

格列本脲对糖尿病及正常大鼠心肌磺脲类药物受体mRNA的影响

OBJECTIVE To exam the glibenclamide added in Shiwei Yuquan capsule .

目的检测十味玉泉胶囊中添加的格列苯脲。

HPLC-FA Study on the Protein Binding of Glibenclamide

格列本脲蛋白结合作用的HPLC-FA法研究

RESULTS Glibenclamide was detected in Shiwei Yuquan capsule .

结果供试品中检出了格列苯脲。

OBJECTIVE To study the pharmacokinetics and bioequivalence of fixed-tablet glibenclamide / metformin in healthy volunteers .

目的研究复方格列本脲片在健康人体内的药物动力学及评价复方格列本脲片相对于格列本脲片与二甲双胍片联用是否具有生物等效性。

After Glibenclamide treatment for 2.5 ~ 6 months , GHb level was reduced to normal range in 31 cases ( 86.1 % ) .

治疗2.5～6个月后，31例病人GHb降至正常或大致正常。

Daily cost of glibenclamide and metformin was low , and gliquidone was medium and rosiglitazone was expensive .

格列本脲、二甲双胍每日药费较低，格列喹酮价格适中，罗格列酮属价格较高品种。

The influence of nifedipine and glibenclamide to plasma glucose level in the fasted and adrenaline hydrochloride induced hyperglycemic rat

硝苯吡啶与格列本脲相互作用对正常大鼠和高血糖大鼠血糖水平的影响

Objective : To develop an RP-HPLC method for the assay of metformin hydrochloride and glibenclamide in compound metformin hydrochloride tablets .

目的：建立HPLC方法测定新药复方盐酸二甲双胍片中盐酸二甲双胍和格列本脲的含量。

Conclusion : The massive dose of FC may be showed an anti-diabetic effect , but its efficiency is still less than that of glibenclamide .

结论：山茱萸发挥抗糖尿病作用需要较大剂量，但效力仍低于优降糖。

The comparative analysis revealed that gliclazide , glurenorm and glibenclamide were the main oral hypoglycemic agents in our hospital .

临床用药量动态分析表明格列齐特、格列喹酮、格列本脲（优降糖）为武汉协和医院主要的口服降血糖药。