G-quadruplexes

G-quadruplexesG-quadruplexes
  1. In this paper , several electrochemical methods were used to study the interactions between G-quadruplexes DNA and derivations of perylene , and binding constants were obtained .

    本论文采用电化学方法,结合光谱方法,主要研究了二萘嵌苯类化合物的性质,及此类化合物与G-四链体DNA之间的相互作用,获得结合模式、结合常数等热力学参数。

  2. Here , fluorescence spectra and energy transfer spectra of five TPM dyes in the presence of G-quadruplexes , single-or double-stranded DNAs were compared .

    本文考察了五种TPM染料和G-四链体、双链和单链DNA作用后的荧光光谱和荧光共振能量转移光谱。

  3. In addition to the familiar duplex DNA , certain G-rich DNA sequences can fold into a variety of four-stranded structures , which are called G-quadruplexes .

    富含鸟嘌呤碱基的DNA序列能够通过鸟嘌呤环的互联作用形成四链螺旋结构,这种结构被称为G-四链体。

  4. The energy transfer fluorescence spectra and energy transfer fluorescence titration can be used to distinguish G-quadruplexes ( including intramolecular and intermolecular G-quadruplexes ) from single-and double-stranded DNAs .

    TPM染料的荧光共振能量转移光谱和荧光共振能量转移滴定可把G-四链体(包括分子内G-四链体和分子间G-四链体)与单链和双链DNA区分开。

  5. The results show that the fluorescence spectra of four TPM dyes can be used to discriminate intramolecular G-quadruplexes from intermolecular G-quadruplexes , single-and double-stranded DNAs .

    结果表明四种TPM染料的荧光光谱可用于区分分子内G-四链体和分子间G-四链体、单链和双链DNA。

  6. In addition to the familiar duplex DNA , certain G-rich DNA sequences can be folded into four-stranded structures , which are made up of four guanine ( G ) bases , and the secondary structures are called G-quadruplexes .

    除了常见的双链DNA,某些富含G碱基的DNA序列通过四个鸟嘌呤环的互联作用可折叠成四链螺旋结构,这样的DNA二级结构被称为G四链体。