CREB

Conclusion : CREB from rat brain tissue involved in brain development process .

结论：CREB参与大鼠脑发育的调节；

The total ERK and CREB had no significant changes .

非磷酸化的CREB和ERK没有显著变化。

However , the effect of estrogen on CREB activity in AD is poorly known .

但是，目前关于雌激素对AD患者中CREB活性的影响的研究很少。

Changes of CREB in brain cortex of ethanol dependent rats and effect of fluoxetine

酒精依赖大鼠皮质CREB变化及氟西汀对其影响

Activation of CREB induced by X rays and its relationship with cAMP signal pathway

X射线诱导CREB活化及其与cAMP通路的关系

CREB peak activity was at 1 hours but it did not return to normal in 12 hours .

CREB的活性在1h即到达峰值，但直到12h并未完全达到正常水平。

As an important nuclear transcription factor , CREB could regulate the process of learning and memory on gene transcription level .

CREB作为一种重要的核转录因子，可在基因转录水平对学习记忆进行调控。

Sodium butyrate up-regulate CD86 molecule on acute leukemia cells partially dependent CREB

丁酸钠部分依赖CREB上调急性白血病细胞CD86分子

Effects of bFGF on expression of CREB in hippocampus and cortex during cerebral ischemia and reperfusion in rats

bFGF对局部性脑缺血再灌注大鼠海马及皮质神经元CREB表达的影响

CREB as a transcriptional regulation factor in eucaryotic cell carries out the function by itself phosphorylation .

CREB是一种细胞核内调控因子，它通过自身磷酸化实现调节转录的功能。

Changes of CREB Protein in Morphine Dependent or Abstinent Rats Studies on Bupivacaine Loaded Sustained-Release Microspheres

吗啡成瘾及戒断大鼠脑内转录因子的改变布比卡因缓释微球的系列研究

Effects of Electro-acupuncture on Learning and Memory and PKA / CREB in the Temporal Lobe of AD Rats

电针对AD大鼠学习记忆能力及颞叶皮层PKA/CREB的影响

The Relationship between CPA Changes with CREB and Dynorphin Gene Expressions in Some Selected Brain Regions of Morphine Dependent Rats

吗啡依赖大鼠CPA建立、消退和重建及部分脑区内CREB和强啡肽基因表达

CAMP response element binding protein ( CREB ) was one of the most important transcription factor , which had important effect on learning-memory .

环磷酸腺苷反应元件结合蛋白（CREB）作为一种重要的核转录因子，在学习记忆中有着重要的作用。

Role of CREB in the regulation of muscarinic m_1 receptor by sarsasapogenin during cell aging

CREB在知母皂苷元调节M1受体中的作用

( 4 ) TCS suppressed Bcl-2 expression through the inhibition of phosphorylated CREB .

TCS抑制的CREB磷酸化对调控Bcl-2基因表达起主要作用。

Effects of Sini Powdered Effective Composition on Hippocampus Neurogenesis and CREB Copy Number in Rats Following Lesions of Olfactory Bulb

四逆散有效部位对嗅球损毁大鼠海马细胞发生及CREB基因拷贝数量的影响

Multiple signal transduction pathways converge on CREB , which plays an essential role in the formation of long-term memory and synaptic plasticity .

CREB是神经元内多条信息传递途径的汇聚点，参与长时记忆形成和突触可塑性。

Experimental Study of the Mechanism of Alleviating Morphine Dependence by a CRE-decoy Oligodeoxynucleotide Competing Against the CREB Binding Site

CREB结合位点诱骗寡核苷酸缓解吗啡依赖机制的实验研究

Effect of Histamine H_3 Receptor Antagonists and Agonists on the Content of cAMP and CREB on Morphine Relapse Rats

组胺H3受体拮抗剂和激动剂对吗啡复吸大鼠cAMP及CREB含量的影响

CREB is a transcription factor , a protein that regulates the expression , or activity , of genes and thus the overall behavior of nerve cells .

转录因子是一种蛋白质分子，会调节基因的表现（性）进而调节细胞的整体行为。

Effects of intrathecal injection of NOS inhibitors on phosphorylated CREB expression in spinal cord of CCD-induced neuropathic pain rats

鞘内注射NOS抑制剂对神经痛大鼠脊髓背角内磷酸化CREB表达的影响

Role of CREB Phosphorylation in Neurogenesis in Vivo Activated by Electro-acupuncture Combined with Repetitive Transcranial Magnetic Stimulation after Focal Cerebral Ischemia

CREB磷酸化在电针结合重复经颅磁刺激激活脑缺血后内源性神经再生的作用机制研究

Conclusion Propofol promotes the proliferation of ANSCs in vitro via up-regulation of phosphorylation level of CREB in ANSCs .

结论异丙酚可能是通过上调细胞中CREB的磷酸化水平从而促进大鼠海马成年神经干细胞的增殖能力。

These results suggested that this kinase may be involved in spermatogenesis by phosphorylating CREB and then stimulate CRE-dependent gene transcription .

这些结果提示TSSK4可能是通过磷酸化CREB，调节CRE依赖的基因转录而参与精子的发生过程。

The results indicate that heat stress can induce CGRP excretion through CREB signal pathway and thus to exert protective roles for hippocampal neurons under ischemic condition .

以上实验结果提示，脑缺血状态下热应激的保护作用可能是通过激活信号蛋白CREB进而促进内源性保护物质CGRP释放而实现。

Conclusion D1 and D3 dopamine receptors can oppositely regulate CREB activation after cocaine treatment and this regulation depends on ERK signaling pathway .

结论D1和D3多巴胺受体对CREB的磷酸化活化起反式调控作用，并且这种反式调控作用依赖于ERK信号通路。

PKA , cAMP and CREB , these signal transduction molecules are related to CRH 's regulated function on the cytokines ' secretion of macrophage .

巨噬细胞内cAMP、PKA和CREB等信号转导分子与CRH调节巨噬细胞的细胞因子分泌有一定关系。

The Effect of Intra-accumbens Injecting Protein Kinase a Inhibitor on Morphine-produced Conditioned Place Preference and the Phosphorylation Levels of CREB in Specific Brain Regions in Rats

伏隔核壳区内注射PKA抑制剂对大鼠吗啡CPP以及部分脑区内CREB的作用

RESULTS Chronic Sini powdered effective composition treatment significantly increased the number of BrdU-labeled cells in the dentate gyrus and hilus of the hippocampus and CREB copy number .

结果四逆散有效部位明显增加了海马齿状回（包括SGZ和hillus区）Brdu标记数量，同时增加了CREB基因拷贝数量。