glucose toxicity

Objective : To study the effects of glucose toxicity on insulin β cells and insulin resistance in type 2 DM .

目的：探讨葡萄糖毒性作用对2型DM胰岛β细胞和胰岛素抵抗的影响。

Conclusion : Glucose toxicity was the key point to induce and accelerate the dysfunction of pancreatic β cells in type 2 diabetes mellitus .

结论：葡萄糖毒性作用是2型糖尿病胰岛β细胞衰竭发生、发展的一个重要环节。

The Effects of the Glucose Toxicity on Expression of TG 、 TPO of Thyroid Cell in Rat

糖毒性对大鼠甲状腺细胞TG、TPO表达的影响

Conclusion NO appears to improve high glucose toxicity induced insulin desensitivity in STZ induced diabetic rats .

结论NO可以改善STZ糖尿病大鼠高糖毒性导致的胰岛素作用下降。

Objective : Our aim was to investigate the relationship between hyperglycemia and glucose toxicity contributing to impaired insulin secretion in type 2 diabetes .

目的：探讨2型糖尿病高血糖与抑制胰岛素分泌毒性作用的关系。

I think this one . Basically , apoptosis is dependent on many factors , for example , glucose toxicity , elevated glucose , too much insulin resistance .

我认为，凋亡取决于很多的因素，例如，葡萄糖毒性、血糖升高以及胰岛素抵抗。

Objective To observe whether nitric oxide ( NO ) improves high glucose toxicity induced insulin resistance in streptozotocin ( STZ ) induced diabetic rats .

目的观察NO能否改善链脲佐菌素（STZ）糖尿病大鼠高糖毒性导致的胰岛素敏感性下降。

Conclusion : Acarbose can improve insulin sensitivity and the endothelial function in poorly controlled type 2 diabetes mellitus with 2 hPG by decreasing high glucose toxicity .

结论：阿卡波糖可能通过降低餐后高血糖，改善机体胰岛素敏感性，使血管内皮功能得到改善，延缓慢性血管并发症的发生与发展。

Insulin is effective , it acts synergistically with oral metformin to reduce glucose toxicity , and it sends the adolescent a message that this is a disease to be taken seriously .

胰岛素治疗有效，可以与二甲双胍口服药产生协同作用，减少葡萄糖毒性，这向青少年传递了一条信息：这是一种需慎重看待的病。

Objective : To study the effects of high concentration glucose on islet cell apoptosis and apoptosis related genes , and discuss the glucose toxicity and its molecular mechanism .

目的：观察高浓度葡萄糖体外对胰岛细胞凋亡及凋亡相关基因表达的影响，探讨葡萄糖毒性及其分子机制。

Whether constant and intermittent high glucose , the injury of oxidative stress and the expression of PKC β 2 , Cav-1 are time-dependent manner . It is suggesting that an early removing of the high glucose toxicity is important .

无论持续性高糖还是波动性高糖，对内皮细胞的氧化应激损伤及PKCβ2、Cav-1表达的影响都具有时间依赖性，提示尽早解除高糖毒性非常重要。