骨髓抑制

A组的骨髓抑制及胃肠反应发生率高于B组（P<0.05）；

Myelosuppression and gastrointestinal tract reaction of group A was more serious than group B ( P < 0.05 );

但CP可引起较严重的毒副作用，如骨髓抑制、出血性膀胱炎、脱发和性腺损害等。

CP may bring about some severe toxicities such as myelosuppression , hemorrhagic cystitis , hair lose and gonad damage .

MA（E）方案的主要毒副作用为骨髓抑制，一般均可耐受。

The suppression of bone marrow was the major side effect .

组不良反应较B组多，主要是化疗后骨髓抑制及消化道反应。

There were more adverse effects in group A than in group B.Most of them were medulla regression , gastrointestinal reaction .

A组的胃肠反应及骨髓抑制明显低于B组。

The occurrence rate of bone marrow suppressed and functional disturbance of gastrointestinal tract of A group was lower than the B group .

两组生活质量改善情况差异有显著性（P0.05）。两组毒副反应相似，主要毒性为骨髓抑制以及胃肠道反应。

The improvement of quality of life was significantly different between the two groups ( P 0.05 ) .

辅以G蛳CSF可防治重度的骨髓抑制，有较好的临床应用价值。

- CSF was used to defend and treat the serious bone marrow restrain , it might have better value .

毒副反应：骨髓抑制方面以VIP为重，EP最轻。

Myelosuppression of VIP regiment was most serious .

实验组胃肠道反应和骨髓抑制较对照组明显减轻，两组间差异有统计学意义（P＜0.05）。

Experimental group , gastrointestinal reactions and bone marrow suppression significantly reduced compared with the control group , the difference between the two groups was statistically significant ( P 0.05 ) .

骨髓抑制为主要的剂量限制性毒性，NP组较TP组稍重，白细胞减少发生率分别为86.7%和67.7%。

The incidence of neutropenia were 86.7 % in NP group , and 67.7 % in TP group .

ECHOP组RR为33.3%，差异有显著性。两组不良反应主要为骨髓抑制以及消化道反应，两组毒副作用差异无统计学意义（p0.05）。

The major toxic effects were bone marrow and digestive reaction , showing no significant difference ( p0.05 ) .

G-CSF治疗肿瘤化疗引起骨髓抑制的临床研究

The Influence on Suppression of Bone Marrow Induced from Using G-CSF by Chemotherapy

GM-CSF和G-CSF治疗化疗后骨髓抑制的疗效比较

Comparative Effect of GM-CSF and G-CSF After Chemotherapy

结论LBP能够促进放疗及化疗引起的小鼠骨髓抑制小鼠的造血功能的恢复。

Conclusion LBP promoted the peripheral blood recovery of irradiation or chemotherapy induced myelosuppressive mice .

CTX毒副作用以感染、骨髓抑制和性腺抑制最严重，使其在临床上的应用受到限制。

The side effect of CTX is infection , arrest of bone marrow and gonadoinhibitory .

复查病例均未发现放射性肺炎及骨髓抑制等严重并发症。结论CT导向下放射性125I粒子组织间植入治疗肺癌安全有效，并发症少，值得推广。

CONCLUSION : CT Guided Radioactive 125I seeds Interstitial Implantation is a safe , effective method with little side effects and worth spread .

结论MVP和VP方案是治疗晚期非小细胞肺癌的有效方案，但MVP组的骨髓抑制较VP组更为严重，因此治疗晚期非小细胞肺癌以VP方案更为理想？

Therefore VP regimen were more preferable in the treatment of advanced non small cell lung cancer .

平和体质的肿瘤患者化疗后可能更容易导致骨髓抑制、寒热表现，其P0.05，有统计学意义。

Normal constitution in cancer patients after chemotherapy may be more likely to cause bone marrow suppression , cold and heat performance , P0.05 , with statistical significance .

G-CSF与GM-CSF联合用药治疗化疗后骨髓抑制的比较

Comparison between Combination of G-CSF and GM-CSF in Patients With Arrest of Bone Marrow Caused by Chemotherapy

中药联合TP方案组Ⅲ～Ⅳ度的骨髓抑制和恶心、呕吐的发生率较国外文献明显降低。

TCM TP group ⅲ - ⅳ bone marrow suppression and the incidence of nausea , vomiting , foreign literature is decreased obviously .

CPE组与CE组的骨髓抑制率分别为71.9%和93.8%（P<0.05）。

The bone marrow suppression rate was 71.9 % in CPE group and 93.8 % in CE group ( P < 0.05 ) .

结论以吡柔比星为主的联合化疗方案治疗高危或难治复发AL疗效较好，但骨髓抑制明显，感染发生率高。

Conclusion Regimens with THP are more effective on treatment of high-risk or refractory and relapsed AL in adults , however , with more serious marrow suppression and higher incidence of infection .

接受化疗的ALL患儿易继发HPVB19感染，并可致骨髓抑制和慢性贫血

Children with ALL who received chemotherapy easily underwent HPV B19 infection , inducing chronic anemia and bone marrow hypoplasia

AL和NHL在初次完全缓解后经4～5次的骨髓抑制性化疗作体内净化后移植。

Before the transplantation , patients with AL and NHL were given marrow inhibition chemotherapy for 4-5 times as vivo purification after the first complete remission .

A组化疗后的毒副反应主要为轻、中度消化道反应和骨髓抑制，经处理后均能恢复，其近期、远期放疗并发症发生率和B组比较，差异无统计学意义（P>0.05）。

In group A , the short-term toxicity and side-effect of neoadjuvant chemotherapy were mainly slight and moderate , and the short-term and long-term radiation complications had no obvious difference between two groups ( P > 0.05 ) .

目的研究黄芪多糖（APS）对MMC致骨髓抑制小鼠的骨髓和脾造血祖细胞生长的影响。

AIM To observe the effect of APS on bone marrow and spleen progenitor cells in MMC induced myelosuppression in mice .

时间（英文）奈达铂（Nedaplatin）在大鼠体内的肾毒性和骨髓抑制的时辰毒理学研究

Medication Time Involved in Nedaplatin-induced Nephrotoxicity and Myelosuppression in the Rats

方法：采用腹腔注射盐酸苯肼和用60Co照射的方法，形成小鼠骨髓抑制性贫血的模型，研究鸡血藤对小鼠的血象影响。

Methods : The aplastis anemia model was established by injecting Phenylhydrazine hydrochloride and irradiating 60 Co ray in mice .

A组骨髓抑制、肝肾损伤较B组未见明显增加。A组轻、中度放射性食管炎的发生率为53.7%（22/41）。

Compared with group B , the side effects including leucopenia and the damage to liver and kidney were not significantly increased in group A and the incidence rate of esophagitis in group A was 53.7 % ( 22 / 41 ) .

粒细胞集落刺激因子（G-CSF）为主治疗化疗所致严重Ⅳ度骨髓抑制临床观察

Clinical Observation of the Treatment Majority with Granulocyte Colony Stimulating Factor ( G-CSF ) for ⅳ Grading Bone Marrow Depression Induced by Chemotherapy