药物不良反应

目的：考察药物不良反应（ADR）致死的规律性。

Objective : To inspect the regularity of death from ADR .

目的分析药物不良反应（ADR）的产生原因，促进临床合理、安全、有效用药。

Objetive Analyzing the reasons for ADR ( adverse drug reaction ), promoting clinical doctors choose reasonable safe and effective drug .

两组治疗耐受性均好，特比萘芬组的药物不良反应发生率2.1%（克霉唑组0.8%，P＞0.05）。

Tolerability was good in both treatment groups , with drug-related cutaneous adverse events in 2.1 % of terbinafine patients and 0.8 % of clotrimazole patients .

观察其复律情况、QT间期及药物不良反应。

The cardiac rhythms , QT duration and side effects of the drugs were observed .

中西组较西医组药物不良反应发生率显著降低（P0.01）。

The adverse reaction rate was significantly lower in TCM-WM group than that in WM group ( P0.01 ) .

目的：对我院1998年1月至2001年6月自发呈报的163例药物不良反应（ADR）报告进行分析。

Objective : To analyze ADR reports of 163 cases from January 1998 to June 2001 in our hospital .

药物不良反应发生率：A组40%，B组9.1%，不需处理且不影响治疗。

40 % patients in group A and 9.1 % patients in group B suffered side effects which need not to be deal with and the side effects also did not influence the treatment .

方法：对我院242例药物不良反应（ADRs）报告作回顾性分析。

Method : 242 cases of ADRs reported in our hospital were analyzed retrospectively .

两药的药物不良反应发生率分别为17.2%和33.0%（P＜0.05）。

The effective rates were much higher for 10 % benzoyl peroxide cream than 5 % benzoyl Peroxide gel ( P < 0.05 ) The adverse reactions to both drugs were 17.2 % , 33.0 % respectively .

方法：采用1次、1d及2周给药方法，观察其药物不良反应。

Methods : The drug was given in a once daily dose for 2 weeks to observe its ADRs .

目的：研究药物不良反应（ADR）所致急性肾损伤的相关因素并探讨其诊疗思路。

Objective : To investigate the related factors of acute renal impairment ( ARI ) induced by adverse drug reactions ( ADRs ) and its therapy .

对消化内科病房181例病人进行了为期7个月的药物不良反应（ADRs）集中监测。

Adverse drug reactions ( ADRs ) monitoring for 181 patients of digestive medical ward have been made during seven months .

结果：112例ADRs报告中最易引起药物不良反应的药物为抗感染药物，占75例（67%）；

Results : Of the 112 reports of ADRs , 75 ( 67 % ) were caused by anti infective agents ;

转变工作模式，为广大患者提供良好的药学服务，开展药物不良反应（ADR）监测等服务。

They should improve their work pattern and reduce medicine price and develop supervising ADR so as to lighten patient ′ s burden and provide pharmacy service .

目的探讨警示性标志在门、急诊输液患者实施药物不良反应（ADR）监测中的作用。

Objective To explore the role of warning mark in monitoring of adverse drug reaction ( ADR ) in fluid infusion in outpatient clinic and emergency department .

结果：2组移植前后血Cr均无明显变化，但A组移植术后排斥反应及药物不良反应发生率显著低于B组（P<001）；

RESULTS : The serum creatinine of 2 groups had no great changes before and after transplantation , but the incidence of rejection and toxicity of group A were lower than that of group B significantly ( P < 0.01 ) .

结果：氟西汀与多虑平治疗后VAS评分较治疗前明显降低（P<0.05），氟西汀组的药物不良反应发生率明显低于多虑平组（P<0.001）。

Results : The VAS values were decreased after treatment in both groups . The incidence of side-effect in fluoxetine-treated group was significantly lower that in doxepin-treated group .

微机药物不良反应监测系统在FOXBASE（VeY2.1）上开发成功，程序呈模块化结构，用户届面直观、查询速度快、功能完善。

A computor system for monitoring adverse reactions of drugs has been developed on FOXBASE ( VeY 2 . 1 ) with a modular construction program .

对105例骨科手术麻醉患者的麻醉用药，药物不良反应（ADRs）及其他不良情况（AEs）进行系统监测。

The use of anesthetic drugs , adverse drug reactions ( ADRs ) and other adverse events ( AEs ) were systematically monitored in 105 patients subjected to anesthesia during orthopedic operation .

结果：3组各失访1例，B组因药物不良反应（ADR）退出2例，C组因ADR退出1例。

Results : One patient were lost to follow up in Group A , B and C , respectively . Two patients in Group B and one patient in Group C stopped the treatment because of severe adverse drug reactions ( ADR ) .

目的：比较静滴阿奇霉素、白霉素与红霉素治疗小儿肺炎支原体（MP）感染的疗效及药物不良反应。

Objective : To compare the effects and adverse reactions of intravenous azithromycin ( AT ), kitasamycin ( KT ) and erythromycin ( ET ) in treating children 's infection caused by mycoplasma pneumonia ( MP ) .

目的：调查门急诊病人静脉滴注使用抗菌药物不良反应（ADR）的发生率、临床表现及相关因素，探讨抗菌药物的合理给药方案。

Objective : To investigate the adverse drug reaction ( ADR ) rates , clinical manifestations and related factors in the outpatients who had been treated with antibacterials by intravenous drip , and to guide rational drug use .

在第4周两组BRMS评分情绪和接触因子之间仍有显著性差异（P<0.01～0.05）。两组药物不良反应发生率之间比较无显著性差异（P>0.05）。

The score of BRMS about emotion and contact presented distinctly difference at the forth week as the rate of adverse reactions had no difference between the two group .

在治疗前及治疗第2、4、8w末采用PANSS评定临床疗效，治疗期间采用TESS评定药物不良反应，并进行比较分析。

The PANSS and TESS were used to assess the curative effects and side reactions before treatment and at the ends of the 2nd , 4th and 8th week of treatment .

目的：研究葛根素注射剂（GGS）引起的药物不良反应（ADR）发生率、ADR类型，探索GGS引起的溶血性贫血（hemolyticanemia，HA）的发生机制。

Objective : To investigate the incidence and profile of adverse drug reactions ( ADRs ) of puerarin injection , and explore the mechanism of Hemolytic Anemia ( HA ) ADR due to puerarin .

合并病毒性肝炎50%，痰菌阳性率41.7%，PPD试验阳性率16.7%，14例抗结核治疗（3HRZE/9HRE）治愈或完成疗程，抗结核药物不良反应发生率为79.2%。

Positive rate of PPD test was 16.7 % . 14 cases treated by anti tuberculosis ( 3HRZE / 9HRE ) were cured or completed the course of treatment . The side effects rate was 79.2 % .

目的：根据上海市药品不良反应监测中心提供的药物不良反应（ADR）报表，分析注射用头孢哌酮钠及其复方制剂引起皮肤及其附属器ADR后的药物治疗方案。

Objective : To investigate the medication for adverse drug reaction ( ADR ) of skin and its accessories induced by cefoperazone sodium injection and its compound preparations according to the reports provided by the ADR monitoring ( center ) of Shanghai .

本文通过对1994～1995年北京地区神经系统用药的回顾性分析，反映出国家正在建立的OTC制度，药物不良反应等因素对北京地区神经系统药物利用趋势的影响。

This article reviewed the drugs used situation of nervous system of Beijing hospitals in 1994 and 1995.It showed the trend and status of the drug utilization influenced by the factors of establishing Chinese OTC system and adverse drug reaction .

监测两组患者治疗前后平均动脉压、血小板凝集率、24h尿蛋白定量，产科并发症和药物不良反应，以此来评价两药疗效。

To compare the effects of the medicine , the followings were recorded before and after the therapy : the mean blood pressure , the agglutination of platelet , the proteinuria in 24 hours , the obstetric complications and the adverse effects of medicine .

为了研究阿糖胞苷（ARA-C）药物不良反应（ADRs）的规律性及其影响因素，对41例使用ARA-C治疗的内科血液病房住院患者（其中白血病患者38例）进行ADRs系统集中监测。

In order to investigate the ARA-C Adverse Drug Reaction ( ADRs ), 41 patients who had received ARA-C in the Department of Hematology ( 38 of them were patients with leukemia ) were studied for ADRs .