聚酮

为研究以合成聚酮高分子寻找高效廉价的催化体系，制备了5%的活性碳负载钯多相催化剂，并首次将其用于催化苯乙烯与CO共聚合成聚酮（PK）的反应中。

In order to search for the efficient and cheap catalyst for the synthesis of polyketone , heterogeneous catalyst of Pd / C was prepared used in the copolymerization of styrene with carbon monoxide as catalyst for the first time .

脂肪族聚酮技术进展

The technical advance in synthesis of aliphatic polyketone

由此推测本实验所采集的红树林土壤样品总DNA中存在有I型聚酮合成酶基因，即这几种红树林土壤中可能含有I型聚酮类天然产物产生菌。

It is indicated that there were type I polyketide synthetase genes , thus , there must be microorganisms that can synthesis type I polyketide compounds in these mangrove soils .

结合其它实验结果提出了一个TMC后PKS线性聚酮链尾部修饰部分生物合成机制的模型。

Combining the results of other experiments , biosynthesis mechanism model of a linear polyketide chain is proposed .

用I型聚酮合成酶基因特异引物对提取出的红树林土壤DNA进行PCR扩增，电泳结果显示被测试的五个土壤样品均有特异性条带。

The DNA extracted from five mangrove soil samples were amplified by PCR using the specific primers for type I polyketide synthetase gene . The electrophoresis results showed that all the five soil samples appeared the typical band of type I polyketide synthetase gene .

一个巨大的多烯抗生素基因簇中聚酮合酶（PKS）基因单元在大肠杆菌中的双重诱导超量表达

Over-expression of a Polyketide Synthase ( PKS ) Module of a Giant Polyene Antibiotic Gene Cluster in E. coli by Double Induction

应用聚合酶链反应得到2株蓝绿藻的毒素聚酮合成酶（PKS）基因，并进行基因序列分析。

Gene of polyketide synthase ( PKS ) from 2 toxin-producing cyanobacteria was prepared by polymerase chain reaction and the gene sequence was analyzed .

从而从正反两面都证明了抗生素AGPM由聚酮途径合成。

Polyketide pathway was therefore confirmed as the main biosynthetic pathways of antibiotic AGPM by evidence both pro and con .

聚酮化合物（PKs）是一类具有生物活性和药用活性的次级代谢产物。为了进一步提高聚酮化合物的产量，异源表达是非常值得尝试的方法。

Polyketides are a diverse class of secondary metabolites with great biological and pharmacological activities . Heterologous expression of polyketide synthase ( PKS ) is a potential approach to improve the production of polyketide .

真菌聚酮合酶分类进展及其应用

The Advance in Classification of Fungal Polyketide Synthases and its Applications

聚酮化合物是一类重要的具有生物活性的次级代谢物。

Polyketides are an extremely important class of bioactive secondary metabolites .

离子液体及其负载化在聚酮合成中的应用

Application of Ionic Liquids and Its Immobilisation in Synthesis of Polyketones

真菌聚酮合酶基因分离方法的研究进展

Advances in the Isolation Methods of Fungal Polyketide Synthase Genes

介绍脂肪族聚酮的结构、性能和应用。

The structure , property and application of aliphatic polyketones are introduced .

利玛原甲藻中聚酮合成酶基因的克隆与表达分析

Cloning and Expression Analysis of PKS Gene in Prorocentrum Lima

新型功能高分子材料&聚酮

New Type Functional Polymer Materials & Polyketone

聚酮合成酶底物专一性的研究进展

Progress in substrate specificity of polyketide synthase

脂肪族高效减水剂的生产工艺新型功能高分子材料&聚酮

Production process of highly efficient aliphatic water reducer New Type Functional Polymer Materials & Polyketone

植物Ⅲ型聚酮合酶的分子机制与应用前景

A comprehensive overview of type ⅲ polyketide synthases from plants : molecular mechanism and application perspective-a review

所以聚酮途径被认为是红曲色素合成的主要途径。

So the polyketide pathway is presumed to be the main biosynthetic pathway of antibiotic monascus pigments .

脂肪族聚酮的应用

Application of aliphatic polyketone

而且它们都具有转化为聚酮合成前体的共同特征。

Besides , these compounds have the same character that all can be transformed to precursors of polyketide biosynthesis .

树脂吸附聚酮反应含钯废液及其重复利用的研究

The study on palladium waste liquid absorbed by resin in the preparation of polyketone and reuse of palladium catalytic system

聚酮化合物是由多种生物，如细菌、真菌、或者植物产生的一类天然产物。

Polyketides are produced by various organisms such as bacteria , fungi , or plants , a subgroup of natural products .

聚酮是一种性能独特的高分子材料，它不仅具有优良的力学性能、耐压、耐高温特性，还具有生物和光降解性能。

The polyketones are a fascinating polymeric material with excellent properties , including mechanical property , pressure tight , high temperature resistance and bio / photo-degradation .

在过去的几年中，从分子遗传学水平对抗生素生物合成的研究进展十分迅速，尤其在聚酮、多肽和氨基糖的研究方面更是硕果累累。

Last few years have seen the rapid and exciting progress towards genetic understanding of antibiotic biosynthesis , especially to that of polyketide , polypeptide and aminosugar biosynthesis .

结果显示这2种肽毒素其保守的聚酮合成酶分析片段二级结构具有较大的相似性，蛋白片段的亲水性与表面可能性区域等特征也极为相似。

The results showed that there are significant similarities in the secondary structure of the analyzed proteins . The two synthetases share nearly identical hydrophilicity and surface probability characteristics .

真菌聚酮合酶在代谢中可催化合成多种具有重要生物学活性的次级代谢物，所以真菌聚酮合酶正逐渐成为药学、食品科学和农学等领域的研究热点。

Fungal polyketide synthases are responsible for the biosynthesis of secondary metabolites such as pigments , mycotoxins , and they are very important in pharmacology , food science and agriculture .

通过正交试验确定聚酮反应的均相体系中催化剂各组分配比和反应条件对催化活性及活性中心寿命的影响。

Using orthonormal experiments , the effect of the amount of each catalyst component and copoly merization condition in the homogeneous phase system of polyketone on the activity and life of catalytic activity center-palladium (ⅱ) was studied .

聚酮化合物的组合生物合成是当前国际化学与生物学交叉学科研究的热点之一，也正在发展成为药物创新超常规的重要手段。

Polyketide compounds and their biosynthesis by combinatorial approaches had received great attention as a cross-disciplinary subject in a new filed of chemical biology for its importance and great potential to create brand new drug in future .