缓释剂

针对这个问题，有各种延长药物作用时间的方法的研究，如巩膜塞、眼内植入物、缓释剂等。

Aiming at this problem , there are all sorts of prolong the therapeutic methods of research , such as the scleral plug , intraocular implants , controlled release formulations .

这项新技术，在国外已在生产上使用，出现了越来越多的缓释剂商品。

This technology has already been used in agricultural production , more and more new products of controlled release formulations appeared .

顺铂缓释剂瘤内治疗大鼠C6胶质瘤实验观察

Efficacy of intratumoral administered cisplatin-impregnated biodegradable polymer for the treatment of C 6 glioma in the rat

犬应用注射缓释剂后1～6个月血药浓度为0.051～0.2μg／ml；

And that of dogs given praziquantel sustained release injections was 0.050-0.2 μ g / ml from 1 to 6 months .

目的：探讨粘膜粘附缓释剂羟丙基纤维素（HPC）与丝裂霉素C（MMC）联合膀胱灌注对MMC在膀胱中保留的效果。

Purpose : To study the effect of mitomycin-c retention in urinary bladder by intravesical instillation of HPC-MMC .

5-Fu缓释剂局部埋植治疗卵巢癌腹膜后转移的实验研究

Experimental study of 5-fluorouracil sustained-release pellet in the treatment of retroperitoneal metastasis of ovarian cancer

术前直肠黏膜下植入5-Fu缓释剂对进展期直肠癌淋巴转移的影响

Impact of Imbedding 5-FU Retarder in Rectum Submucosa Preoperation to Lymphatic Metastasis in Progression of Rectal Cancer

目的本研究用溶剂挥发法制作了环孢霉素A（CyclosporineA，CsA）微粒体缓释剂。

Objective Microspheres containing cyclosporine A ( CsA ) were prepared using a solvent evaporation process .

结论bFGF在以纤维蛋白为缓释剂条件下，对移植脂肪具有良好的促增殖作用。

Conclusion bFGF with fibrinogen as its carrier of sustained delivery favors the survival of fat graft and weight increase .

彩超引导下经皮穿刺~（125）Ⅰ粒子联合5-FU缓释剂植入治疗肝门区肿瘤

Ultrasound-guided percutaneous implantation of radioactive seed ~ ( 125 )ⅰ and slow-released 5-FU in treating hilar hepatic tumor

结果：（1）纤维蛋白胶MTX缓释剂的药物释放与纤维蛋白浓度有关。

Results : The release of MTX was related to the concentration and bio degradation of fibrin glue .

DDVP缓释剂熏杀长尾黄鼠寄生蚤的现场实验

A Field Trial of the Control of Fleas on Citellus undulatus by Fumigating with DDVP Slow-releasing Pellets

目的研究卡氮芥-聚乳酸（BCNUPLA）缓释剂在体内的抑瘤作用。

Objective To study effectiveness of controlled release polymers of BCNU and polyactic acid ( BCNU - PLA ) against rat glioma .

联合治疗组、MWA组脾脏指数较5-FU缓释剂组、对照组高，P0.05。

The spleen index in combination group , MWA group were higher than that in 5-FU sustained-release implants group and control group , P0.05 .

C组手术：开腹分离胆管制造狭窄同B组，待狭窄制造完成后，在局部放置中人氟安（5-FU的缓释剂），关腹。

Group C surgery : open separation of the bile duct manufacturing narrow with group B Upon completion of the narrow manufacturing , placed in the local human the fluoride security ( 5-FU release formulation ), the abdomen was closed .

目的：比较文拉法辛缓释剂（XR）与速释剂（IR）治疗抑郁症的疗效及不良反应。

Objective : To study the efficacy and side effects of venlafaxine extended release ( XR ) and venlafaxine immediate release ( IR ) in the treatment of depression .

对照组只给予微波消融治疗，联合组患者微波消融后均在超声引导下植入5-FU缓释剂。

The patients were treated by microwave ablation in the control group , and the patients ( combining therapy group ) were treated by the 5-FU sustained-release implants after microwave ablation .

结果：浓度为04mg/ml的红比霉素和阿克拉霉素术中一次应用效果较好，结膜下注射5-FU高分子缓释剂较5-FU针剂效果好，副作用小。

Results : ? Daunorubicin or aclacinomycin at a dose of 0.4 mg / ml had better effect promoting filtration bleb . 5-FU polymer had better effect and less complications than 5-FU .

方法（1）5FU缓释剂的体外释放实验和体外抑瘤实验：测定浸出液药物的浓度，计算释放量；

Methods ( 1 ) In vitro experiments , the releasing action and anti-tumor effect of slow-release 5-FU were studied .

以DDVP缓释剂药丸在实验室及野外对不同变态期的长尾黄鼠寄生蚤进行了杀灭试验。

Laboratory and field tests were conducted for the control of fleas on Citellus undulatus in their various metamorphotic stages with DDVP slow-releasing pellets .

将5-FU缓释剂瘤内植入治疗组、术后行5-FU静脉化疗组和对照组。

3.69 cases with unresectable pancreatic carcinoma were divided into 3 groups randomly : intra-tumor embedding of slow-released 5-FU treated group , intravenous injection of 5-FU continued in treaed group and control group .

Closantel缓释剂驱除山羊实验感染肝片吸虫的效果

Effect of Closantel Sustained Release Bolus to Goats Experimentally Infected with Fasciola hepatica

CD8+T淋巴细胞则降低，联合治疗组、MWA治疗组与5-FU缓释剂治疗组、对照组比较均有统计学意义，P0.05。

But the CD8 + T lymphocyte were decreased , the combination group , MWA group compared with 5-FU sustained-release implants group , control group were statistically significant , P0.05 .

结论瘤内注射5-Fu-NPs缓释剂的抗肿瘤效果优于局部和全身单纯5-Fu给药，它具有较重要研发价值。

Conclusion The antitumor effect of intratumoral administration of 5-fluorouracil-loaded polyactic acid is better than that of local and systemic administration of 5-Fu alone .

结论鼻黏膜下植入5-Fu缓释剂是鼻乳头状瘤患者术后辅助治疗的最佳方法之一，可有效防止复发，值得借鉴使用。

Conclusion One best method of schneiderian membrane under implants of 5-Fu Slows release the medicinal preparation assists the treatment after the nose papilloma patient technique , but effectively prevents recurs , is worth profiting from uses .

目的：探讨125I植入+5-氟尿嘧啶缓释剂瘤内注射对中晚期胰腺癌患者的临床疗效。

Objective : To evaluate the therapeutic effect of intra-tumor implanted of Iodine - ~ ( 125 ) seeds with intra-tumor injection of slow-release 5-Fluorouracil ( 5-Fu ) on advanced pancreatic carcinoma .

联合治疗组、MWA组及5-FU缓释剂治疗组的肿瘤重量均小于对照组，P0.05，抑瘤率分别为78.79%、42.90%、26.75%。

The tumors weight in combination group , MWA group and 5-FU sustained-release implants group were lighter than that in control group , P0.05 , the tumor-inhibition rates were 78.79 % , 42.90 % , 26.75 % .

5FU缓释剂瘤内注射组肿瘤组织中炎症反应和血管内膜增厚程度明显高于其他各组（P<0.05）。

The extent of local inflammation and increase in thickness of blood vessel endothelium were more evident in the treatment groups than in the other groups ( P < 0.05 ) .

提示Closantel缓释剂对驱除实验感染肝片吸虫有一定效果，在虫体感染前投药会起到预防作用。

It suggest that sustained release closantel has limited helminthic effect to Fasciola hepatica , but It can be used for prevention before infection .

研究了4个龙眼品种果实的结冰点及其影响因素，比较了-1℃冰温和3℃低温贮藏对石硖龙眼贮藏效果的差异，探讨了冰温贮藏龙眼时SO2缓释剂的最适用量。

The freezing point of longan fruits and its affecting factors were determined in four cultivars . The effects of ice temperature ( - 1 ℃) storage and normal low temperature ( 3 ℃) storage and different dosage of SO_2 Releaser on fruit quality were investigated in this paper .