竞争性抑制

最佳pH值为7.7。结论：高浓度表面活性剂对酶表现非竞争性抑制作用；

Optimum pH is 7.7 . Conclution : Higher concentration of surfactant showed a non - competitive inhibition on the lipase activity ;

久效磷、对硫磷与大鼠血影细胞温育，对血影细胞AChE呈竞争性抑制。

Monocrotophos and parathion with AChE in the ghosts of rats showed competitive inhibition .

氯仿－乙醇混合液（2∶3／v∶v）对该酶的抑制属于非竞争性抑制。

The inhibition of the mixture of chloroform-enthanol ( 2 ∶ 3v / v ) on this enzyme is noncompetitive .

Dox非竞争性抑制Tet-激活的P-gpATPase活性。

Moreover , Dox inhibited Tet-activated P-gp ATPase activity in a noncompetitive manner .

实验表明：GM1对兔红细胞膜钠泵有激活作用，而GM3则为非竞争性抑制作用，Vm发生改变而Km不变。

The results indicate that GM1 activates the sodium pump , but GM3 is a non-competitive inhibitor of the sodium pump in rabbit red cells .

最后，胞外全长片段的选择素竞争性抑制选择素介导的细胞粘附的效率比短片段Lec／EGF要高。

Finally , extracellular selectin constructs were more potent than Lec / EGF in competitive inhibition selectin mediated cell adhesion .

动力学研究表明，在不同Na~+、K+浓度对，GM3对Na~+、K~+-ATP酶的抑制作用，均呈非竞争性抑制。

Kinetics studies of Na + , K + - ATPase showed that GM3 acted as a non-competitive inhibitor when the concentrations of Na + , K + and ATP changed .

竞争性抑制实验测定了去水吗啡和经典抗精神病药的IC（50）和Ki值。

Producing a half-maximal inhibition ( IC50 ) and dissociation constant of the receptor-antagonist interaction ( Ki ) of apomorphine and some classical antipsychotic drugs were measured by competitive binding of labelled and unlabelled ligands .

槲皮素竞争性抑制CYP3A2右美沙芬N脱甲基反应，非竞争性抑制CYP2E1氯唑沙宗6羟化反应。

QU exhibited competitive inhibition of CYP3A2 dextromethorphan N-demethylation reaction and expressed noncompetitive inhibition of CYP2E1 chlorzoxazone-6-hydroxylation reaction .

Cl－对底物CDNB有竞争性抑制作用，对GSH是非竞争性抑制作用；

The kind of inhibition by Cl - is competitive for CDNB and non competitive for GSH , respectively .

抑制特征曲线表明Rg1和Rg2对MAO-B的抑制作用均属竞争性抑制。

The inhibition of MAO-B by Rg_1 and Rg_2 showed competitive nature . No effect of Re on MAO-B was observed .

本文研究了十二种黄酮类化合物对兔心肌中环磷酸腺苷磷酸二酯酶（cAMP-PDE）的动力学，表明它们都属于竞争性抑制类型的，并且还给出了它们的抑制常数Ki值；

The inhibition kinetic study of 12 flavonoids on the cAMP-PDE in rabbit heart muscle indicates that the inhibition is competitive .

三维结构显示，该抑制剂专一地结合于RG的活性位点，占据RG的底物结合部位，为竞争性抑制机制提供了结构依据。

This inhibitor anchors exclusively in the active site of RG by competition with its natural substrate , providing structural evidence for a competitive inhibition mechanism .

结果显示SPC（高粱原花青素）对α-淀粉酶具有明显的抑制作用，抑制的机理是通过可逆的竞争性抑制来实现的，其抑制常数Ki是2.71mg/ml。

Results showed that the activity of α - amylase was obviously inhibited by SPC via reversible competitiveness , the constant of inhibition ( Ki ) was 2.71mg/ml .

BP为一种氨基酸衍生物，具有抑制肾阴离子转运的功能，通过竞争性抑制作用，阻碍PAPM进入肾皮质细胞，减少其肾毒性。

And BP which derived from amino-acid effected as a renal anion-transport inhibitor for the purpose of reducing the renal toxicity of PAPM by inhibiting PAPM into renal cortex cells through competitive with PAPM in membrane transport .

当四种底物为饱和浓度时，aphidicolin对模板-引物表现为反竞争性抑制。

An uncompetitive inhibition was observed at varied template-primer concentrations and saturated concentration of dNTPs .

正常及模型动物Tc-NGA体内动态显像99m研究表明正常动物较肝损害动物血本底清除快，且此显像能被NGA竞争性抑制；

The liver imaging of normal and model animals showed that the rates of blood clearance of normal animals were higher than that of liver injured model animal and the imaging could be inhibited by excessive NGA ;

目的探讨重组人促黄体激素释放激素-绿脓杆菌外毒素A（LHRH-PE40）在胃癌细胞及正常细胞是否存在相应受体表达及存在竞争性抑制。

Objective To study whether luteinizing hormone-releasing hormone aeruginosa exotoxin 40 ( LHRH-PE40 ) can be expressed in the gastric carcinoma cells or the normal cells and detect the competitive inhibition .

通过Lineweaver-Burk法考察了DNJ降血糖活性的抑制类型，结果表明DNJ对蔗糖底物和麦芽糖底物的α-葡萄糖苷酶抑制类型均为混合竞争性抑制。

In addition , the type of DNJ inhibition of hypoglycemic activity was investigated by Lineweaver-Burk method , and the results showed that DNJ as a α - glucosidase inhibitor displayed a mixed competitive inhibition mechanism . 4 .

结果：大豆皂苷具有很强的α葡萄糖苷酶抑制作用，且表现为非竞争性抑制作用。

Results : Soyasaponins showed potent inhibitory activities against α - glucosidase .

反竞争性抑制的非稳态酶动力学布尔函数图解研究

Studies on Non-Steady State Enzyme Kinetics of Uncompetitive inhibition

酶底物动力学分析表明，马桑内酯对该酶的抑制属非竞争性抑制。

The enzyme substrate kinetic analysis indicated that it was the noncompetitive inhibition .

它们也竞争性抑制引起疾病的“坏”细菌。

They can also out-compete " bad " bacteria that may cause disease .

葡萄糖的存在对纤维素酶产生非竞争性抑制作用。

The existence of glucose brings non-competitiveness inhibition .

结果表明：野靛碱和苦豆碱对羧酸酯酶活性有显著的抑制，为可逆抑制类型的非竞争性抑制作用；

The results indicate that cytisine and aloperine could inhibit carboxylesterase activity through non-competitive inhibition .

连续搅拌反应器中产物&底物非竞争性抑制动力学的无因次分析

Non-dimensional Analysis of Non-competitive Substrate-Product inhibition Dynamics

本实验采用酶联免疫印迹和竞争性抑制实验识别大豆制品中的致敏蛋白。

Study on the yeast scp production by using of wastewater from production of soybean product ;

结论枸杞多糖对α-葡萄糖苷酶具有较强的抑制作用，抑制机理为非竞争性抑制。

CONCLUSION LBP is a stronger α - glucosidase inhibitor . Its inhibitive mechanism is noncompetition inhibition .

同时选择非竞争性抑制进行了试验验证和常数求解。

At the same time , inhibition kinetic constant of noncompetitive inhibition is testified by force of a experiment .

建立了固定化纤维素酶的反应动力学模型，该模型以米氏方程为基础并考虑了产物竞争性抑制的影响。

A kinetics model was developed for predicting and simulating immobilized cellulase performance , which follows Michaelis_Menten kinetics with competitive product inhibition .