环肽

某些环肽及其相应线型肽在不同溶剂中构象的CD谱研究

Study on the Conformation of Three Cyclic Peptides and Their Correspondent Linear Peptides with CD Spectroscopy

Mannich型环肽的液相及固相合成比较

Comparative Synthesis of Mannich-Type Cyclopeptides between Solution-Phase and Solid-Phase Protocols

用FITC标记的鬼笔环肽标记F-肌动蛋白，分别用荧光显微镜和流式细胞仪技术分析肌动蛋白细胞骨架的重组情况；

Cellular F-actin stained with FITC-phalloidin was examined by fluorescence microscopy and flow cytometric analysis .

目的获得具交叉保护性的抗细菌脂多糖（LPS）多克隆抗体与模拟LPS多表位的噬菌体展示环肽克隆。

Objective To prepare polyclonal anti-LPS antibody with cross protection against LPS from different bacteria and to screen mimotopes of LPS from cyclic 7-mer phage peptide library .

海洋环肽噻唑氨基酸片断（D-Val）Thz的合成

Synthesis of the marine cyclopeptide thiazole amino acid component ( d-val ) thz

用F-actin特异的荧光探针罗丹明-鬼笔毒环肽对微静脉染色和激光共聚焦显微镜技术观察微静脉内皮肌动蛋白细胞骨架的改变。

The venular F-actin filaments were detected by staining with rhodamine phalloidin and observed under laser confocal scanning microscope .

应用固相多肽合成了BQ-123和3个环肽，结构经质谱鉴定正确。

BQ-123 and 3 cyclopeptides were synthesized by solid-phase peptide synthesis ( SPPS ) . The structures were established by MS.

共分离得到了31种化合物，其中18种新成分，17种为番荔枝内酯（annonaceousacetogenins）类化合物，另一个为含九个氨基酸的环肽。

31 compounds were isolated , among which 18 were new constituents including 17 new annonaceous acetogenins and a cyclopeptide .

采用Fmoc固相合成法得到直链肽，通过空气氧化两个半胱氨酸的巯基生成二硫键，得到一类新型含二硫键的环肽。

A novel disulfide bond-bearing cyclopeptides has been designed and synthesized by means of air oxidation of bis ( S-Acm ) which was synthesized through Fmoc solid-phase synthesis .

实验利用显微镜观察，鬼笔环肽（phalloidin）-FITC标记和流式细胞仪技术分析转换培养基与未转换培养基的SHEE细胞。

Using the technologies of microscopy and phalloidin-FITC labeling and flow cytometry , SHEE cell was tested passing by accordant and alterative culture medium .

FK228具有特殊的缩酯环肽结构，可有效透过细胞膜，通过抑制组蛋白去乙酰酶而显示良好的抗肿瘤活性。

FK228 with a special depsipeptide may efficiently pass through the cellular membrane and exert a prominent anti-tumor activity by inhibiting histone deacetylase .

前言：目的：对金铁锁中的环肽成分进行系列研究。

Objective : To study the cyclic peptides from Psammosilene tunicoides .

自组装巯基环肽单层膜修饰金电极电化学行为的研究

Study on Cyclic Peptides Containing Benzene and Cystine Modified Au Electrode

石竹科植物环肽研究进展

Progress in chemistry of cyclic peptides from plants of Caryophyllaceae

抗癌环肽药物放线菌素D新类似物的化学全合成研究

Total Chemical Synthesis of Three Novel Actinomycin D Analogs Used as Antitumor Drugs

自组装环肽纳米管介导的药物跨膜转运及其抗肿瘤活性研究

Studies on Trans-membrane Drug Transportation Mediated by Self-assembling Peptide Nanotubes and Anti-tumor Activities

环肽及非肽类内皮素受体拮抗剂的研究

The Study of Cyclopeptide and Nonpeptide Endothelin Receptor Antagonists

二茂铁类环肽的合成与分子识别研究

Synthesis of a Family of Ferrocene-bearing Cyclo-pseudo-peptides by Liquid Method and Molecular Recognition

海洋环肽Phakellistatin13的全合成研究

Total Synthesis of A Marine Cyclopeptide : Phakellistatin 13

无机磷试剂辅助均环肽库的建立及其电喷雾质谱研究

Construction and ESI-MS Analysis of Homocyclic Peptide Libraries Assisted by Inorganic Phosphorus Reagents

酵母双杂交随机环肽库的构建、鉴定与扩增

Construction , identification and amplification of a yeast two-hybrid random cycle peptide library

环肽的分析方法与研究

Analysis Method and Research in Cyclopeptides

新型含二硫键的环肽的合成

Synthesis of Novel Disulfide Bond-Bearing Cyclopeptides

含多胺、二硫键以及硫醚结构的环肽的设计合成及分子识别研究

Studies on Design , Synthesis and Molecular Recognition of Cyclic Peptides Containing Polyamine , Disulfide or Thioether Structure

生物活性环肽与相应线性肽相比在生物体内具有更好的抗酶解和抗化学降解能力。

Compared with linear peptides , the degradative capabilities and anti-enzymatic hydrolysis ability of biological cyclopeptide is better .

概述了近六年来海绵环肽化合物及其所具有的主要生理活性的研究进展；

This paper reviews cyclic peptides from marine sponges and their biological activities in the last six years .

在无机磷试剂辅助下建立了氨基酸自组装成均环肽的方法，得到了相应的均环肽库。

Homocyclic peptide libraries were constructed by self-assembly of amino acids with the assistance of inorganic phosphorus reagents .

目的：构建含16个氨基酸的酵母双杂交随机环肽库。

AIM : To construct a cycle peptide library composed of 16 random amino acids with yeast two hybrid system .

络合Ca~（2+）的Au/巯基环肽自组装单层膜的交流阻抗研究

Research of electrochemical impedance spectroscopy on self-assembling cyclic peptide membrane bonded Ca ~ ( 2 + ) supported by gold

环肽特殊的结构特点以及在化学及药学上的优势使其成为当今化学中发展迅速、具有挑战性的领域。

Cyclopeptide with special architecture and useful functions in chemistry and pharmaceutical chemistry is a new challenging field that is quickly developing .