氯硝西泮

目的：探讨氯硝西泮对持续性TD的临床作用。

Objective : To study effect of clonazepam on persistent tardive dyskinesia ( TD ) .

结论：采用反相HPLC法准确、灵敏、简便，适用于氯硝西泮的血药浓度测定及临床药动学研究。

CONCLUSION : The RP-HPLC method is sensitive , accurate simple and suitable for determination of the concentration of clonazepam in serum and for the clinical pharmacokinetics research .

丙米嗪组显效率为50%，总有效率75%，2组疗效差异无显著意义（P＞0.05），氯硝西泮组不良反应较丙米嗪组少。

Adverse reactions of clonazepam group were less than imipramine group .

氯硝西泮抗惊厥作用耐受及停药后大鼠脑内NMDA受体放射自显影观察

Autoradiography of NMDA receptors in amygdala kindled rats with tolerance to and dependence on the anticonvulsant effect of clonazepam

血、尿中氯硝西泮及其代谢物7-氨基氯硝西泮的GC-ECD法检测

Determination of clonazepam and 7-amino clonazepam by GC-ECD in human plasma and urine samples

目的：研究氯硝西泮（clonazepam，CZP）对丙戊酸钠（Sodiumvalproate，VPA）的药代动力学及药效学的影响。

OBJECTIVE : To study the effect of clonazepam ( CZP ) on the pharmacokinetics and pharmacodynamic of sodium valproate ( VPA ) .

目的探讨氟西汀联用氯硝西泮治疗惊恐障碍前后状态&特质焦虑问卷（STAI）测查结果变化特点。

Objective To explore the changes of STAI before and after medication on panic disorder with fluoxetine plus clonazepam .

采用相溶解度法考察羟丙甲纤维素（HPMC）和聚维酮（PVP）对水溶液中氯硝西泮与羟丙基-β-环糊精（HP-β-CD）包合作用的影响。

The phase solubility method was used to investigate the influence of HPMC and PVP on the inclusion effect of clonazepam and hydroxypropyl - β - cyclodextrin in aqueous solution .

Klonopin（仿制药：氯硝西泮）（0.5mg的）：这是一个长效苯二氮类，多年来我最有效的药物。

Klonopin ( generic : clonazepam )( 0.5mg ): This is a long acting benzodiazepine , and my most effective drug over the years .

高效液相色谱法检测癫痫患儿血清中氯硝西泮

RP - HPLC assay for serum clonazepam in epileptic children

红霉素对氯硝西泮药代动力学的影响及其机理的研究

Influence and mechanism of erythromycin on the pharmacokinetics of clonazepam

氯硝西泮、654-2联合治疗海洛因依赖

Combined use of clonazepam and 654-2 in the treatment of heroin dependence

硝西泮、氯硝西泮甲基衍生物的气相色谱-质谱分析

Analysis of Methylated Derivatives of Nitrazepam and Clonazepam by Gas Chromatography-Mass Spectrometry

大鼠血清及脑组织中氯硝西泮药物浓度的变化

Study on changes of clonazepam 's concentration in rat brain and serum

LC/MS法测定氯硝西泮的有关物质

Determination of clonazepam ′ s related substances by LC-MS

氯硝西泮口腔崩解片的研制及质量评价

Preparation and quality evaluation of clonazepam orally disintegrating tablets

对氯硝西泮注射液现行质量标准中鉴别测定方法的建议

Suggestion on Identification of Clonazepam Injection in Current Standard

氯硝西泮针剂与片剂治疗焦虑性神经症的比较

Clonazepam injection vs tablet in treatment of anxiety disorder

氯硝西泮治疗强迫症的双盲对照试验

A controlled double-blind trial of clonazepam in treating obsession

结果：该胶囊中检出氯硝西泮。

Result : Clonazepam was found in the capsule .

奎硫平联合氯硝西泮治疗精神分裂症急性兴奋80例

Treatment of 80 Cases of Schizophrenia Manifesting Acute Erethitic Symptoms with Quetiapine Combined with Clonazepam

结论低周波治疗仪治疗失眠症的疗效优于氯硝西泮。

ConclusionThe silver spike point therapy has the better curative effect on insomnia than Clonopin .

氯硝西泮治疗精神运动性兴奋与氟哌啶醇的比较

Clonazepam vs haloperidol in treating psychomotor agitation

氯硝西泮抗大鼠听源惊厥耐受性的受体学基础

Receptor base on tolerance of the antiepileptic effect to clonazepam in the audiogenic seizure rats

氯硝西泮治疗持续性迟发性运动障碍

Persistent Tardive Dyskinesia Treated with Clonazepam

氯硝西泮治疗社交恐怖症

Clonazepam in treating social phobia

氯硝西泮重复给药可有效地控制惊厥复发，但也可引起药物在体内的蓄积。

Repeated administration of CZP would avoid this , but might lead to drug accumulation in the body .

结论：氯硝西泮肌注治疗酒精所致精神障碍的兴奋疗效肯定，副反应轻。

Conclusion : Clonazepam has a rapider effect and gentler side effects for the treatment of alcoholic psychotic disorder .

目的：评价利培酮配合氯硝西泮注射液治疗偏执型精神分裂症的疗效。

Objective : To evaluate the efficacy of risperidone combined with clonazepam injection in the treatment of paranoid schizophrenia .

结论：氯硝西泮治疗强迫症安全、有效。

CONCLUSION : It is suggested that Clo is a safe and effective drug in the treatment of obsession .