巨核细胞

抗凋亡蛋白Bcl-xL在巨核细胞分化中的作用及其在原发性血小板增多症巨核细胞分化中表达的研究

The Role of Antiapoptotic Bcl-x_L during Megakaryocyte Differentiation and in Essential Thrombocythemia

原代培养5～7d后贴壁细胞呈梭形成纤维样细胞和圆形巨核细胞。

There were two types of adherent cells after 5 to 7 days primary culture , fibroblast-like cells and round megakaryocyte .

可见巨核细胞，红细胞岛和粒细胞前体细胞

Note the presence of megakaryocytes , erythroid islands , and granulocytic precursors .

流式细胞术分析人正常骨髓巨核细胞DNA含量和倍体性分布

Analysis of Megakaryocyte Nuclear DNA Content and Ploidy Distribution in Human Normai Bone Marrow by Flow Cytometry

~（60）Coγ辐射对小鼠巨核细胞集落生成单位增殖分化的影响

Effect of ~ ( 60 ) Co γ - rays on proliferation and differentiation of CFU-Meg in mouse

ITP患者T细胞对巨核细胞生成作用的影响

The Effects of T Cells Patients with ITP on Megakaryocytopoiesis

GM-CSF体外促进多倍体巨核细胞的生成

Enhancement of the Formation of Megakaryocyte Ploidy by GM - CSF in vitro

益髓灵初提物对白血病巨核细胞系HI－Meg增殖与分化影响的研究

The effect of Yi Sui Ling on the proliferation and differentiation of a leukemic megakaryocyte cell line hi-meg

目的探讨小肠RNA在促进肠道辐射损伤恢复的同时对受照射小鼠粒系和巨核细胞系损伤的恢复作用。

Objective To explore the restorative effect of intestinal RNA on injuries of granulocyte and megakaryocytic series in mice after abdominal γ - irradiation .

人血小板因子4（HumanPlateletFactor4，简称hPF4）是一种发现于骨髓巨核细胞和血小板α-颗粒的蛋白质。

Human platelet factor 4 ( hPF4 ) is a protein found in megakaryocytes and platelet α - granules .

诱导巨核细胞成熟治疗复发性ITP疗效观察

Observation of effect of inducer megakaryocyte mature on the treatment of recurring idiopathic thrombocytopenic purpura

尽管临床上PV以红细胞增多为主，但骨髓分析显示此病有红系、粒系、巨核细胞系三系增生。

PV was characterized by erythrocytosis , but in most cases , there were erythrocytosis , guanulocytosis and thrombocytosis in bone marrow .

目的探索肝素能否增强血小板生成素（Tpo）刺激巨核细胞生成。

Objective To verify whether heparin could enhance the stimulating effect of Tpo on megakaryocytopoiesis .

采用ABC免疫细胞化学染色法检测巨核细胞GATA-1和NF-E7的表达水平。

Immune cytochemistry was used to detect GATA - 1 and NF-E2 in megakaryocytes .

实验通过原位分子杂交技术，检测人骨髓巨核细胞分化发育过程中神经生长因子（NGF）基因表达情况。

The expression of nerve growth factor ( NGF ) gene during development of megalocaryocytes was studied by in situ hybridization .

BMFCM联合IL11促进成熟巨核细胞生成的效果更佳。

The effect of BMF-CM combined with IL-11 on the expansion of mature megakaryocytes was further enhanced .

用Percoll密度梯度及免疫磁珠法分离骨髓巨核细胞；

Percoll density gradient and immunomagnetic beads methods were used to purify megakaryocytes from bone marrow .

细胞免疫化学法检测巨核细胞MPL。

Immune cytochemistry was used to detect MPL on megakaryocyte .

该结果显示，人巨核细胞增殖受多种造血生长因子调控，其中TPO是特异地调控人巨核祖细胞生长的一种细胞因子。

The results suggested that megakaryocytopoiesis was regulated by several cytokines and that TPO was a megakaryocytic lineage specific cytokine .

结果高、中、低剂量的TPO成熟肽组动物的血小板数、巨核细胞集落数和骨髓DNA含量均明显高于TPON－端结构域蛋白的相应组（P＜0.01）。

The results showed that platelet number , CFU Meg and DAN content in TPO mature peptide were remarkably higher than that of APO N terminal domain protein in different dosage groups .

PF4是造血负性调控因子，它是血细胞生成的抑制剂，特别是对巨核细胞的生成。

PF4 can inhibit newborn blood vessel production and is a negative regulator of hematopoiesis .

而其中的白血病化疗后血小板减少患者和AA患者的骨髓巨核细胞数较TPO正常组显著降低。

Bone marrow megakaryocytes ( MK ) count in after chemotherapy AL and AA patients were lower than those with normal serum TPO levels controls .

应用抗血小板膜糖蛋白抗体、免疫组织化学技术、对10例骨髓增生异常综合征（MDS）骨髓活检组织中巨核细胞（MK）进行了观察。

N immunohistochemical study was performed on trephine biopsy specimens of bone marrow in 10 patients with myelodysplastic syndromes ( MDS ) .

本文对124例MDS和136例AL患者的骨髓象巨核细胞计数及形态改变观察结果进行了分析。

In this paper , the cellular count and morphologic change of bone marrow megakaryocytes in124 patients with myelodysplastic syndrome ( MDS ) and136 patients with acute leukemia ( An ) were analyzed .

方法对ITP患者进行骨髓巨核细胞光镜与电镜检查，并作了治疗前后对比。

Methods : We observed the changes on bone marrow megalokaryocytes ( microscope and electroscope ) in20 patients with ITP before and after the treatment .

目的：免疫性血小板减少性紫癜（ITP）是常见的小儿出血性疾病，以出血及外周血小板减少，骨髓巨核细胞正常或增多并伴有成熟障碍为主要表现。

Objective : Immune thrombocytopenic purpura ( ITP ) is a common hemorrhagic disease during children , which main manifestation is hemorrhage and peripheral plate-reduction .

结论：CD41标记的SAP染色可以显著提高巨核细胞检出率；且对老年贫血具有一定的鉴别诊断价值。

Conclusion : CD41 labelled SAP staining obviously increases the detection rate of megakaryocyte , which is valuable for differential diagnosis of senile anemia .

血浆块法检测巨核细胞集落（CFU-MK）的形成；

Colony forming unit-megakaryocyte ( CFU-MK ) was detected by plasma clotting assay ;

目的探讨血小板生成素（TPO）和巨核细胞计数对特发性血小板减少性紫癜（ITP）患儿预后的意义。

Objective To explore the prognosis of idiopathic thrombocytopenic purpura ( ITP ) in serum levels of thrombopoietin ( TPO ) and number of megakaryocyte .

目的探讨急性巨核细胞白血病（FAB-M7）以外的急性髓细胞白血病（AML）患者化疗期间一过性不典型巨核细胞增生（AMH）现象。

Objective : To describe the finding of atypical megakaryocytic hyperplasia ( AMH ) during chemotherapy for AML other than acute megakaryoblastic leukemia .