修复酶

DNA修复酶系统的研究&Ⅰ.紫外线诱发~3H-TdR在着色性干皮病淋巴细胞中的非合成期掺入

Study of AND Repair Enzyme System I. Ultraviolet-Induced H-TdR Unscheduled Incorporations Xeroderma Pigmentosum Lymphocytes

焦炉工代谢酶和DNA修复酶基因多态性与DNA损伤的关系

Association of metabolic and DNA repair enzyme gene polymorphisms and DNA damage in coke-oven workers

DNA切除修复酶的表达及与肺癌预后的关系

Expression of DNA excision repair enzymes and lung cancer prognosis

DNA光修复酶的功能及其在化妆品中的应用

Function of DNA Photolyase and Its Application in Cosmetic

DNA光修复酶体外活性的研究

The activity of DNA photolyase in vitro

DNA修复酶的结构和功能

Structures and functions of DNA repair enzymes

DNA修复酶在胃癌组织中的表达变化及临床意义

Study on the Expression of DNA Repairing Enzyme in the Gastric Carcinoma and Its Clinical Significance

DNA修复酶基因多态性与肺癌易感性研究进展

A Review of Research on the Relationship between Polymorphisms of DNA Repair Genes and Lung Cancer Susceptibility

白藜芦醇下调线粒体DNA修复酶对重症急性胰腺炎大鼠胰腺腺泡细胞凋亡的影响

Resveratrol induces mitochondrial DNA repair enzyme downregulation and promotes pancreatic acinar cell apoptosis in rats with severe acute pancreatitis

局灶性脑缺血再灌注早期DNA单链损伤与DNA修复酶APE/Ref-1表达变化的实验研究

Experiment on DNA single-strand damage and expression change of DNA repair enzyme APE / Ref-1 after focal cerebral ischemia / reperfusion

本文就肺癌易感性与其相关的DNA修复酶基因多态性的国内外研究进展作一简要介绍。

The review gave a brief for studies in genetic susceptibility to lung cancer and related polymorphism of DNA repair genes .

DNA修复酶是一类能保护生物体免受各种DNA损伤的毒性效应和保证遗传信息完整性的重要酶蛋白。

DNA repair enzymes have evolved to protect prokaryotes and eukaryotes from the mutagenic effect of DNA damage and preserve genomic integrity .

应用多因素Logistic回归分析，对在食管癌发生中代谢酶基因与修复酶基因的交互作用以及环境-环境、基因-环境的交互作用进行了分析。

The interaction between genes and environmental risk factors was analyzed by multivariate logistic regression model .

DNA损伤修复酶参与修复VCM所致的DNA损伤。

DNA damage repair enzymes take part in the repairing of DNA damage induced by VCM .

近年来，分子生物学研究进一步提示DNA损伤修复酶的异常改变（多态变体）可能是决定食管癌高易感性的重要分子基础。

The molecular studies further indicate that alteration of DNA repaired enzyme ( polymorphism ) may play an important role in human carcinogenesis .

DNA加合物及其相关修复酶基因多态性在COPD发病中的研究

Study on the Roles of DNA Adducts and Genomic Polymorphisms of Associated Repair Genes in the Pathogenesis of COPD

DNA修复酶（MGMT）在人胃肠癌中表达的临床意义

Clinical significance of MGMT expression in human gastroenteric cancer

目的研究DNA光修复酶（EC4.1.99.3）对紫外光幅射产生的嘧啶二聚体修复的作用机制。

Aim To study the mechanism of Escherichia coli DNA photolyase ( EC 4.1.99.3 ) in repairing the ultraviolet induced pyrimidine dimmer lesions in DNA .

研究表明脑缺血再灌注早期DNA修复酶的表达减少可能与随后发生的细胞死亡有关。

It has been reported that early decrease of DNA repair enzyme probably has correlation with subsequent DNA-damaged cell death after cerebral ischemia / reperfusion .

DNA修复酶（MGMT）在胃癌中表达与病理类型及转移的相关性

Expression of MGMT in gastric cancer and its relationship with pathological types and metastasis

单细胞凝胶电泳测肝细胞DNA损伤，免疫组化法测肝脏DNA损伤修复酶的表达。

DNA damage of liver cells was detected by single cell gel electrophoresis . The expressions of DNA damage repair enzymes were measured by immunohistochemical methods .

大肠杆菌DNA光修复酶（photolyase）的表达纯化及其活性研究

Expression , Purification and Biological Activity of E.coli DNA Photolyase

介绍苯致血液毒性两大类主要的易感性标记物、代谢酶，DNA修复酶及其多态性；

This review is focused on two main types of markers of susceptibility to benzene-induced hematotoxicology , metabolizing enzymes , DNA repairing enzymes , their polymorphisms are also addressed .

顺铂对A549细胞DNA修复酶MGMT和DNA-PKcs表达的影响

Effects of Cisplatin on Expression of DNA Repair Genes : MGMT and DNA-PKcs in A549 Cells

广西肝癌高发区氧化性DNA损伤与修复酶hOGG1的表达和多态性关系的研究

Detection of oxidative DNA damage , hOGG_1 expression and polymorphisms in hepatocellular carcinoma at endemic regions in Guangxi

目的研究胶质瘤体外药物敏感性与肿瘤细胞DNA修复酶O6-甲基鸟嘌呤-DNA-甲基转移酶（MGMT）的表达之间的相关性。

Objective To study the relationship between O6-methylguanine-DNA-methyltransferase ( MGMT ) expression in gliomas and in vitro sensitivity of gliomas to chemotherapy .

[目的]检测肺癌组织中DNA损伤修复酶MGMT、DNAPKcs和Ku的表达变化，探讨其表达和肺癌发生发展及临床病理特征之间的关系。

To detect the expression of DNA repair enzymes : MGMT , DNA PKcs and Ku in lung cancer and normal tissues to evaluate their roles in lung cancer progression .

在TNFα诱导L929细胞凋亡过程中，细胞核内的DNA修复酶poly-（ADP-ribose）polymerase（PARP）未被降解。

During the course of TNF α - induced cell death , the DNA repair enzyme , poly ( ADP-ribose ) polymerase ( PARP ) was not degraded .

Karnes等发现COX-2蛋白在缺乏错配修复酶、MSI（+）的结直肠癌组织中表达明显减少。

By immunohistochemistry staining , Karnes found that the expression of COX-2 protein reduced in colon cancer with MSI ( + ) .

黄曲霉毒素（aflatoxin，AFT）是环境致癌物研究的热点之一，而抑癌基因、修复酶基因及代谢酶基因多态性与肿瘤易感性的关系也很受重视。

Aflatoxin ( AFT ) was highly concerned in the study of environmental carcinogens . And the relationship between genetic polymorphisms and susceptibility to cancer attracted more attention too .