三螺旋
- 网络Triple Helix;triple-helix;Triplex;H-DNA
-
目的:探讨末端标记8-甲氧基补骨脂素(8-MOP)的三螺旋结构寡核苷酸(TFO)对鸭乙肝病毒(DHBV)-DNAX/C区一目标基因的特异结合及定位损伤作用。
Objective : To study the method of specially combing and damage to duck hepatitis virus ( DHBV ) - DNA X / C region by triple helix form oligonucleotide ( TFO ) which was labelled with 8-methoxypsoralen ( 8-MOP ) at3 ' end ( TFO-P ) .
-
本章还将利用三螺旋模型的概念来解释美国国家创新系统内不同机构主体之间交互作用的增加。
The triple helix model has been introduced to explain the increasing of interaction among multiple organizations in the innovation system .
-
溴代胞嘧啶对三螺旋DNA稳定性的影响
Influences of substitution of bromide cytosine on stability of triplex DNA
-
三螺旋DNA分子久期方程的约化
Reduction of the secular equation for triple & helical DNA
-
三螺旋DNA的应用。
Secondly , triplex DNA application .
-
它与DNA或RNA杂交特异性很强,可与靶基因形成稳定的三螺旋结构。
It binds to complementary RNA or DNA with specificity and form a triplex complex with highly stability .
-
傅立叶红外光谱(FTIR)分析表明其存在三螺旋结构。
Fourier-transform infrared ( FTIR ) investigation showed the existence of helical arrangements of collagen .
-
这种三螺旋体的稳定性极高,以至于在同型嘧啶PNA靶向双链DNA嘌呤道时,能取代其中一条DNA链侵入双螺旋。
The stability of these triple helixes is so high that homopyrimidine PNA targeted to purine tracts of dsDNA invades the duplex by displacing one of the DNA strands .
-
三螺旋结构寡核苷酸序列对DHBV基因的连接及封锁抑制作用研究
Inhibitory effect of triple helix forming oligonucleotide on binding and inhibition of DHBV gene
-
反义寡核苷酸对基因表达的抑制作用可通过多种不同机制而实现:①抑制基因转录,即反义寡核苷酸与DNA双螺旋分子的特定序列结合形成三螺旋DNA以阻止基因的转录。
The inhibiting mechanism of the antisense oligonucleotides on gene expression is as followed . ( 1 ) Inhibition of the gene transcription antisense oligonucleotides can bind to specific sequence of double-strand DNA and form triple-helical DNA to inhibit the transcription .
-
通过圆二色谱(CD)和吸收光谱研究了Cu(2+)对三螺旋poly(A:2I)的解旋行为,并从结构的角度分析了其解旋机理。
The behaviour of unwinding of the triple helix poly ( A : 2I ) induced by Cu2 + was investigated by circular dichroism and ultraviolet spectra methods , and the mechanism of unwinding was analysed from the structure view point .
-
由此,本文根据科普产业的产业特征,结合媒体、非政府组织和公众对科学传播的重要影响,对科普产业协同创新主体进行拓展,提出媒体NGO公众构成的新三螺旋创新模式。
Thus , the paper developed the innovation subjects and proposed new triple-helix model of " media-NGO-public ", according to the characteristics of popular science industry and the important influence on science communication come from the media , non-governmental organizations and public .
-
三螺旋蛋白质中孤立子的温度效应
The temperature effect by the soliton in the three-helix protein molecules
-
三螺旋理论是继国家创新系统之后新出现的理论模型。
The triple helix theory come forth after national innovation system .
-
三螺旋链蛋白质运动模型的行波精确解组
Traveling wave accurate solutions to Tri-helix chain protein movement model
-
三螺旋形成寡核苷酸抑制乙型肝炎病毒复制及抗原合成的实验研究
Inhibitory effect of triplex forming oligodeoxynucleotides on HBV replication and synthesis of antigen
-
同心三螺旋线合金流动性测定仪的研制及应用
Development and Application of Instrument with Three Concentric Spiral Lines for Determining Alloy Flowability
-
创新研究的三螺旋模型:概念、结构和公共政策含义
Triple Helix Model in Innovation Research : Concept , Structure and Public Policy Implication
-
双三螺旋:创新与可持续发展
Triple Helix Twins : Innovation and Sustainability
-
羟化脯氨酸对于在生理条件下形成稳定的胶原三螺旋是必需的。
Proline hydroxylation under physiological conditions in the formation of stable collagen triple helix is essential .
-
三螺旋理论视野中的科技创新&基于美国创业型大学的分析
Scientific Innovation in " Triple Helix Model " & Based on the Analysis of Entrepreneurial Universities in America
-
胶原是胞外基质的主要成分,具有独特的三螺旋结构。
Collagens , characterized by a unique triple-helical structure , are the predominant component of extracellular matrices ( ECMs ) .
-
是否存在着第四个螺旋的问题已成为大学产业政府三螺旋争论的焦点之一。
Debate over the university-industry-government triple helix model has focused on the question of whether there is a fourth helix .
-
在这样的背景下,基于三螺旋理论的区域创新模式应运而生。
Under such a background , there is an emergence of regional innovation mode based on the triple helix theory .
-
作为三螺旋之外的第四方,社会中介组织可能作为第四螺旋起着越来越重要的作用。
As the fourth power besides the triple helix , the intermediaries may play a more and more important role .
-
这两个三螺旋创新模型共同构成了科普产业协同创新发展生态系统的一体两翼。
Those two triple-helix innovation models form the " One Body Two Wings " collaborative innovation ecosystem of the popular science industry .
-
特别是对关于区域创新模式的三螺旋理论进行了拓展与突破。
Particularly , we succeeded in the development and breakthrough of a regional innovation model named as " triple helix theory " . 2 .
-
基于三螺旋理论的政产学研合作模式与机制研究
Study on the Mode and Mechanism of the Cooperation of Government , Industry , University and Research Institute Based on the Triple Helix Theory
-
对于大学本身而言,学术资本机制是大学参与到蝶形三螺旋中进行创业的微观动力基础。
For the University itself , academic capital Mechanisms is the basis of micro-power for the universities involved in the " butterfly triple helix " .
-
根据三螺旋演进培养模式,在培养高端人才过程中,大学与产业应在合作中充分发挥培养人才的作用,并由政府提供有力支撑。
According to triple helix evolution cultivation mode , universities and industries should cooperate and be fully functional , and governments should provide a strong support .